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ProteomicsCdc48’s interactions play a role in the cellular oxidative response in an aging-dependent manner
The cellular redox status has long been linked to different cellular functions, including protein quality control (PQC) and aging. The prominent molecular machine Cdc48 (p97/VCP in mammals) is one of the key players involved in PQC, shuttling misfolded proteins to degradation. Through a range of N-t...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-05-28 | PXD045122 | Pride
Redox Yeast Aging 
TranscriptomicsMicroarray analysis of the brain in a mouse model of cerebral ischemia/reperfusion injury treated with human paraoxonase 1 against vehicle control
Paraoxonase 1 (PON 1) binds to high-density lipoprotein (HDL) and is responsible for its anti-atherosclerotic effect through its antioxidant activity. This dataset contains gene expression data obtained from a study investigating the effects of human paraoxonase 1 treatment on acute ischemic stroke ...
ORGANISM(S): Mus musculus 
2025-06-05 | E-MTAB-14182 | biostudies-arrayexpress
UnknownCommunity-engaged mHealth intervention to increase uptake of HIV pre-exposure prophylaxis (PrEP) among gay, bisexual and other men who have sex with men in China: study protocol for a pilot randomised controlled trial.
Not available
S-EPMC9092176 | biostudies-literature
GenomicsThe androgen receptor induces a distinct transcriptional program in castration resistant prostate cancer in man
The androgen receptor (AR) is the major transcriptional driver of prostate cell growth in man. For the first time, we define AR targets in prostate cancer (PC) tissue representing progression from treatment-naive to castrate-resistant disease (CRPC). We employed chromatin immunoprecipitation with hi...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-28219 | biostudies-arrayexpress
UnknownPregnancy Outcomes in Youth With Type 2 Diabetes: The TODAY Study Experience.
Not available
S-EPMC4686849 | biostudies-literature
GenomicsEGAS00001000262-sc-2023-03-27T08:52:54Z - samples
This dataset includes Illumina EPIC Capture Sequencing Data of 376 samples from 188 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy, with matched pathologically assessed non-cancer control material. This DNA methylation data includes donors and samples incl...
EGAD00001010184 | EGA
GenomicsEGAS00001000262-sc-20140722 - samples
To characterize the subclonal genomic architecture of androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of 51 tumours from 10 patients to an average sequencing depth of 55x, including multiple metastases from different anatomic sites in each patient and, in fiv...
EGAD00001000891 | EGA
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsThe Natural History of Human Prostate Cancer - samples
Affymetrix SNP6.0 genotype data for prostate cancer patients
EGAD00010000498 | EGA
GenomicsEGAS00001000262-sc-20160408 - samples
To characterize the subclonal genomic architecture of non-androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of pelvic lymph node metastases and matching noncancerous blood from 10 patients to an average sequencing depth of 55x. The patients are part of PELICAN ...
EGAD00001002002 | EGA
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