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To validate the FOX flash photolysis system for hydroxyl radical footprinting of proteins experiments, TNF-alpha was oxidized in the presence and absence of a specific monoclonal antibody, adalimumab. The peptides that show decrease in oxidation correlate well with the known epitope for adalimumab.
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD023169 | Pride
Protein post-translational modifications (PTMs) are key modulators of protein structure and function that often change in a dynamic fashion in response to cellular stimuli. Dynamic post-translational modifications are very challenging to structurally characterize using modern techniques, including c...
ORGANISM(S): Gallus gallus (Chicken) 
2023-01-16 | PXD037050 | Pride
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