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MetabolomicsSilage-derived flavonoids reprogram rumen microbiota to improve milk fat synthesis via rumen-mammary gland axis

Inoculation with homofermentative lactic acid bacteria (LAB) effectively enhances the silage quality of forages. Moreover, feeding such LAB-inoculated silage modulates rumen microbiota composition and metabolites, thereby improving ruminant production performance. Nevertheless, the specific mecha...

2026-01-11 | MTBLS13651 | MetaboLights
MetabolomicsCoupling between high-resolution mass spectrometry and focalized data-analysis methods provides the identification of new putative glycosidic non-anthocyanic flavonoids in grape

INTRODUCTION: The biochemical diversity of flavonoids is based on glycosylation, methylation, acylation, and many other modifications of the flavonoid backbone. Liquid chromatography coupled to high-resolution mass spectrometry demonstrated to be a powerful approach to gain new i...

2022-06-29 | MTBLS4202 | MetaboLights
MetabolomicsMetabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3, and BGLU4 in glycosylation of various flavonoids

Flavonoids are specialized metabolites that play important roles in plants, including interactions with the environment. The high structural diversity of this metabolite group is largely due to enzyme-mediated modifications of flavonoid core skeletons. In particular, glycosylation with different ...

2025-02-25 | MTBLS1965 | MetaboLights
MetabolomicsUntargeted metabolomics of purple and orange-fleshed sweet potatoes reveals a large structural diversity of anthocyanins and flavonoids

Anthocyanins are economically valuable phytochemicals of significant relevance to human health. Industrially extracted from multiple fruit and vegetable sources, anthocyanin yield and profiles can vary between sources and growing conditions. In this study, we focused on three purple-fleshed and o...

2021-09-01 | MTBLS2956 | MetaboLights
MetabolomicsAccumulation Characteristics of Flavonoids and Contribution to Antioxidant Capacity in Wild and Cultivated Kiwifruits

This study aimed to clarify flavonoids accumulation characteristics and their contribution to antioxidant capacity in wild type (WT) kiwifruit (Actinidia deliciosa) and three cultivated varieties (Xuxiang, XX; Yazui, YZ; Hongyang, HY). Integrating untargeted metabolomics and traditional biochemic...

2026-01-14 | MTBLS13683 | MetaboLights
MetabolomicsElucidations on the structures of some putative flavonoids identified in postharvest withered grapes (Vitis vinifera L.) by quadrupole time-of-flight mass spectrometry
Grape dehydration is an oenological process used for production of high-quality reinforced and sweet wines. High-resolution mass spectrometry (ultrahigh-performance liquid chromatography/quadrupole time-of-flight [UHPLC/QTOF]) was used to deepen the characterization of some flavonoids previously pro...
2021-12-09 | MTBLS1804 | MetaboLights
MetabolomicsEnhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids
The notion that plants use specialized metabolism to protect against environmental stresses needs to be experimentally proven by addressing the question of whether stress tolerance by specialized metabolism is directly due to metabolites such as flavonoids. We report that flavonoids with radical sca...
2013-12-06 | MTBLS57 | MetaboLights
MetabolomicsComprehensive analysis of flavonoids metabolism and transcription in different parts of Houttuynia cordata

Houttuynia cordata is a medicinal plant with diverse pharmacological activities, but the relationship between its flavonoid components and gene expression across different plant parts remains poorly understood. This study aims to explore these relationships using metabolomics and transcriptomics ...

2026-01-24 | MTBLS12311 | MetaboLights
MetabolomicsTranscriptome and metabolome changes in Chinese cedar during cold acclimation reveal the roles of flavonoids in needle discoloration and cold resistance

Cryptomeria fortunei growth and development are usually affected by low temperatures. Despite the evergreen nature of this species, most needles turn yellowish-brown in cold winters. The underlying discoloration mechanisms that cause this phenomenon in response to cold acclimation remain...

2022-08-12 | MTBLS3184 | MetaboLights
MetabolomicsOrgan-specific accumulation of flavonoids and terpenoids in Myricaria laxiflora based on non-targeted metabolomics
Background Myricaria laxiflora, an endangered species endemic to the water-level fluctuation zone of the Yangtze River, plays a critical role in riparian ecosystem conservation. However, a comprehensive understanding of its organ-specific metabolic composition remains scarce. Method A non-targeted m...
2026-04-24 | MTBLS14367 | MetaboLights
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