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TranscriptomicsEngineering Material Properties of Transcription Factor Condensates to Control Gene Expression in HEK-293T Cells
Phase separation of biomolecules into condensates is a key mechanism in the spatiotemporal organization of biochemical processes in cells. We systematically engineered light-inducible transcription factor condensates with different material properties and analyzed their influence on transcription ac...
ORGANISM(S): Homo sapiens 
2024-04-01 | E-MTAB-13905 | biostudies-arrayexpress
TranscriptomicsMicroarray profiling of polyploid macrophage progeny
To explore how bacterial lipoproteins (i.e. TLR2 ligands) increased macrophage ploidy via mitotic defects, we performed global analysis of cell cycle gene expression changes induced by bacterial lipoproteins. FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of th...
ORGANISM(S): Mus musculus 
2016-10-27 | E-MTAB-5085 | biostudies-arrayexpress
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