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UnknownMolecular and phenotypic evaluation of a novel germline TMEM127 mutation with an uncommon clinical presentation.
Not available
S-EPMC5741081 | biostudies-literature
TranscriptomicsTranscription profiling of mouse metaphase II oocytes collected from 5-6 week old mice with those collected from 40-42 week old mice
Decreasing oocyte competence with maternal aging is a major factor in human infertility. To investigate the age-dependent molecular changes in a mouse model, we compared the expression profiles of metaphase II oocytes collected from 5-6 week old mice with those collected from 40-42 week old mice usi...
ORGANISM(S): Mus musculus 
2004-09-01 | E-MEXP-150 | biostudies-arrayexpress
TranscriptomicsEstrogen-Related Receptor M-NM-3 (ERRM-NM-3) Regulates Oxygen-Dependent Expression of Voltage-gated Potassium (K+) Channels and Tissue Kallikrein during Human Trophoblast Differentiation
Estrogen-related receptor M-NM-3 (ERRM-NM-3) serves a critical O2-dependent regulatory role in differentiation of human cytotrophoblasts to syncytiotrophoblast. In this study, we investigated expression of genes encoding tissue kallikreins (KLK1) and voltage-gated K+ channels (KV7) during differenti...
ORGANISM(S): Homo sapiens 
2013-04-30 | E-GEOD-46463 | biostudies-arrayexpress
TranscriptomicsRegions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region
Background Sex chromosomes are subject to evolutionary pressures distinct from the remainder of the genome, shaping their structure and sequence content. We are interested in the sex chromosomes of domestic pigs (Sus scrofa), how their structure and gene content compares and contrasts with other mam...
ORGANISM(S): Sus scrofa 
2012-08-30 | E-GEOD-40244 | biostudies-arrayexpress
TranscriptomicsGenomic alterations of chromosome 11 induce transcriptomic dysregulation in aggressive and malignant prolactin tumours
Pituitary tumors are generally considered as benign. However, many are invasive (45 to 55%) and some are described as aggressive with a high proliferation rate and short post-operative time to recurrence and 0.2% metastasize. The molecular events associated to the progression of the pituitary tumor ...
ORGANISM(S): Homo sapiens 
2011-03-16 | E-GEOD-22615 | biostudies-arrayexpress
TranscriptomicsPreparation of archival formalin-fixed paraffin-embedded mouse liver samples for use with the Agilent gene expression microarray platform
For decades, formalin-fixing and paraffin embedding (FFPE) has been routinely used to preserve tissue samples for histological analysis.M-BM- Global gene expression analysis of these archival tissues has the potential to greatly advance research attempting to link perturbations in molecular pathways...
ORGANISM(S): Mus musculus 
2013-02-28 | E-GEOD-40990 | biostudies-arrayexpress
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