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TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (old mouse liver)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43173 | biostudies-arrayexpress
TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (young mouse liver)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43171 | biostudies-arrayexpress
TranscriptomicsRAP1 protects from obesity, diabetes and metabolic syndrome through its extra telomeric role regulating gene expression (young mouse white fat)
RAP1 is one of the components of shelterin, the capping complex at chromosome ends or telomeres. Unlike other shelterins, however, RAP1 is not essential for preventing telomere fusions. RAP1 also binds along chromosome arms, where it is proposed to regulate gene expression. To investigate the non-te...
ORGANISM(S): Mus musculus 
2013-06-21 | E-GEOD-43172 | biostudies-arrayexpress
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Hair regeneration]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58153 | biostudies-arrayexpress
TranscriptomicsSox4 links tumor suppression to accelerated aging in mice [Telogen]
Sox4 is a transcription factor expressed during embryonic development and some adult tissues such as lymphoid organs, pancreas, intestine and skin. During embryogenesis, Sox4 regulates the survival of mesenchymal and neural progenitors, lymphocyte and myeloid differentiation, and pancreatic, bone an...
ORGANISM(S): Mus musculus 
2015-05-20 | E-GEOD-58154 | biostudies-arrayexpress
UnknownMultiphysics simulations reveal haemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanics.
Not available
S-EPMC11652225 | biostudies-literature
UnknownClinical Impact of Prosthesis Oversizing in Self-Expanding Intra-Annular Transcatheter Aortic Valve Replacement
Not available
S-EPMC12613009 | biostudies-literature
UnknownImpact of Diabetes on 10-Year Outcomes Following ST-Segment-Elevation Myocardial Infarction: Insights From the EXAMINATION-EXTEND Trial.
Not available
S-EPMC9851431 | biostudies-literature
UnknownAdiposity markers and lung function in smokers: a cross-sectional study in a Mediterranean population.
Not available
S-EPMC5148852 | biostudies-literature
UnknownMulticentric randomized clinical trial to evaluate the long-term effectiveness of a motivational intervention against smoking, based on the information obtained from spirometry in primary care: the RESET study protocol.
Not available
S-EPMC4743363 | biostudies-literature
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