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TranscriptomicsMolecular Cytogenetic Analysis of a Gliosarcoma with Osseous Metaplasia
Gliosarcoma, a rare glioblastoma variant, is composed of a glial and a mesenchymal component. Though the mesenchymal portion most commonly resembles a fibrosarcoma, other differentiation patterns have been observed. We present the first genomic characterisation (karyotyping followed by FISH and arra...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-25411 | biostudies-arrayexpress
TranscriptomicsGenomic Aberrations in Paediatric Gliomas and Embryonal Tumours
The pathogenesis of paediatric central nervous system tumours is still poorly understood. In an attempt to increase the knowledge of the genetic mechanisms underlying these tumours, we performed genome-wide screening of 17 paediatric gliomas and embryonal tumours using a combination of G-band karyot...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-27671 | biostudies-arrayexpress
TranscriptomicsComparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents
Leydig cells (LCs) are the primary androgen producing cells in males throughout development and appear in chronologically distinct populations; fetal Leydig cells (FLCs), neonatal LCs and adult Leydig cells (ALCs). ALCs are responsible for progression through puberty and for maintenance of reproduct...
ORGANISM(S): Homo sapiens 
2017-04-18 | E-MTAB-5453 | biostudies-arrayexpress
TranscriptomicsSpecific Genomic and Transcriptomic Aberrations in Tumors Induced by Partial Hepatectomy of a Chronically Inflamed Murine Liver [aCGH]
Background & Aims. Resection of hepatocellular carcinoma (HCC) tumors by partial hepatectomy (PHx) is associated with promoting hepatocarcinogenesis. We have previously reported that PHx promotes hepatocarcinogenesis in the Mdr2-knockout (Mdr2-KO) mouse, a model for inflammation-mediated HCC. Now, w...
ORGANISM(S): Mus musculus 
2015-04-01 | E-GEOD-61423 | biostudies-arrayexpress
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