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TranscriptomicsHigh-throughput pyrosequencing of miRNAs from Medicago truncatula nodules and roots
We have used deep sequencing of small RNAs from nodules and root apexes of the model legume Medicago truncatula, to identify 113 novel candidate miRNAs. These miRNAs (legume or Mt-specific) are encoded by 278 putative hairpin precursors in the M. truncatula genome. Several miRNAs are differentially ...
ORGANISM(S): Medicago truncatula 
2009-07-07 | E-GEOD-15438 | biostudies-arrayexpress
TranscriptomicsThe small RNA diversity from Medicago truncatula roots under biotic interactions evidences the environmental plasticity of the miRNAome
Plants show a remarkable plasticity to adapt their root architecture to biotic and abiotic constraints of the soil environment. Although some of these modifications are fine-tuned by miRNAs, there are still shadow zones in these regulations. In the model legume Medicago truncatula, we analyzed the ...
ORGANISM(S): Medicago truncatula 
2014-08-15 | E-GEOD-49226 | biostudies-arrayexpress
UnknownNerve compression and pain in human volunteers with narrow vs wide tourniquets.
Not available
S-EPMC4436908 | biostudies-literature
TranscriptomicsTranscription profiling of Pseudomonas PAO1 cultures supplemented with PQS
Virulence factor production and the development of biofilms in Pseudomonas aeruginosa have been shown to be regulated by two hierarchically organised quorum sensing (QS) systems via small acyl-homoserine lactone (AHL) signal molecules. Recently, a third bacterial signal molecule, the Pseudomonas qui...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2008-11-07 | E-GEOD-3836 | biostudies-arrayexpress
ProteomicsProteome wide measurements of protein half-lives in Mycoplasma pneumoniae
We obtained proteome wide measurements of protein half-lives in M. pneumoniae by performing pulse-chase experiments following SILAC methods. We estimated degradation rates of individual proteins by measuring the increase in light protein compared to heavy protein labeling along the growth curve.
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2020-11-24 | PXD016386 | Pride
Degradation rates Protein half-life Silac 
TranscriptomicsGene expression of HCT116 cells after stimulation with oncostatin M (OSM)
To evaluate gene expression profiles in intestinal epithelial cells (IEC) after OSM stimulation, we have employed whole genome microarray expression profiling as a discovery platform to identify relevant genes which are potentially of interest to reveal the role of OSM in intestinal inflammation. T...
ORGANISM(S): Homo sapiens 
2014-12-13 | E-GEOD-53295 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of mouse liver cells
We generated the individual transcriptomes of 96 liver cells using the Fluidigm C1 platform. In brief, a suspension of cells was prepared from the liver of a 14-week old B6CastF1 (C57Bl/6J mother x CAST/Ei father) female mouse and loaded onto a 10-17 m C1 Single-Cell Auto Prep IFC (Fluidigm), and ce...
ORGANISM(S): Mus musculus 
2016-02-08 | E-MTAB-3707 | biostudies-arrayexpress
TranscriptomicsRNAi profiling by array of human WPMY-1 cells with PPARbeta/delta knock down and exposure to PPAR agaonists
Human WPMY-1 cells were depleted for PPARbeta/delta and exposed to the PPAR agonists GW501516.
ORGANISM(S): Homo sapiens 
2010-12-31 | E-MEXP-2756 | biostudies-arrayexpress
TranscriptomicsThe glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens
Breakdown products of some glucosinolates M-bM-^@M-^S defense chemicals of Brassicales M-bM-^@M-^S induce detoxifying enzymes and demonstrate preventive activities against chemically induced tumorigenesis in animal models. However, other breakdown products are genotoxic. 1-Methoxy-3-indolylmethyl al...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-61494 | biostudies-arrayexpress
TranscriptomicsExpression profiling, Lin-9 depletion array in D3 mES cells
Lin-9 was depleted in ES-D3 cells (ATCC CRL-1934) and the resulting expression profile changes mapped via microarrays
ORGANISM(S): Mus musculus 
2013-05-13 | E-MTAB-1490 | biostudies-arrayexpress
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