Sort   by:  
 Page size 
GenomicsTranscriptional profiling of embryos lacking Flvcr1
Transcriptional profiling of embryos lacking Flvcr1
PRJNA913440 | ENA
TranscriptomicsTranscriptional profiling of embryos lacking Flvcr1
Flvcr1 is a heme transporter involved in multiple processes. Here we invetigated the role of this transporter in brain development in mice. Deletion of Flvcr1 in nerual progenitors leads to metabolic collapse of neural progenitors and cortical disruption. Using transcriptional profiling, we show tha...
ORGANISM(S): Mus musculus 
2024-06-27 | GSE221231 | GEO
GenomicsTranscriptonal response of mammalian cells lacking FLVCR1 to choline depleted or replete media conditions
Transcriptonal response of mammalian cells lacking FLVCR1 to choline depleted or replete media conditions
PRJNA948356 | ENA
ProteomicsDysregulation of FLVCR1-dependent mitochondrial calcium handling in neural stem cells causes congenital hydrocephalus.
Congenital hydrocephalus (CH), occurring in approximately 1/1000 live births, represents an important clinical challenge due to the limited knowledge of underlying molecular mechanisms. The discovery of novel CH-genes is thus essential to shed light on the intricate processes responsible for ventric...
ORGANISM(S): Homo sapiens (Human) 
2024-08-09 | PXD047897 | Pride
Calcium handling Mass spectrometry Flvcr1 
TranscriptomicsTranscriptonal response of mammalian cells lacking FLVCR1 to choline depleted or replete media conditions
Integrative genetic analysis identified FLVCR1 as a choline transporter in mammalian cells. We profilied the transcriptional response of HeLa cells with and without FLVCR1 to choline depeleted or replete conditions.
ORGANISM(S): Homo sapiens 
2023-08-08 | GSE228126 | GEO
ProteomicsMitochondrial energetic failure underlies FLVCR1-related sensory neuropathy
Genetic pain loss disorders represent a heterogeneous group of rare diseases mainly characterized by defective nociception. Understanding the underlying molecular mechanism is fundamental to improve the treatment of patients affected by these rare disorders. Feline Leukemia Virus Subgroup C Receptor...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD071580 | Pride
Posterior column ataxia and retinitis pigmentosa  pcarp  retinitis pigmentosa  hereditary sensory and autonomic neuropathy  hsan  heme  choline  mams  mercs 
UnknownMutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa.
Not available
S-EPMC2978959 | biostudies-literature
UnknownComprehensive mapping of receptor-functioning domains in feline leukemia virus subgroup C receptor FLVCR1.
Not available
S-EPMC1367145 | biostudies-literature
UnknownIntegrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.
Not available
S-EPMC10367582 | biostudies-literature
UnknownA splice-site variant in FLVCR1 produces retinitis pigmentosa without posterior column ataxia.
Not available
S-EPMC5841564 | biostudies-literature
Sort   by:  
 Page size