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MetabolomicsMetabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly positive mode)

Large-scale metabolite annotation is a challenge in liquid chromatogram-mass spectrometry (LC-MS)-based untargeted metabolomics. Here, we develop a metabolic reaction network (MRN)-based recursive algorithm (MetDNA) that expands metabolite annotations without the need for a comprehensive standard...

2019-03-22 | MTBLS612 | MetaboLights
MetabolomicsMetabolic reaction network-based recursive metabolite annotation for untargeted metabolomics (Aging fruit fly negative mode)

Large-scale metabolite annotation is a challenge in liquid chromatogram-mass spectrometry (LC-MS)-based untargeted metabolomics. Here, we develop a metabolic reaction network (MRN)-based recursive algorithm (MetDNA) that expands metabolite annotations without the need for a comprehensive standard...

2019-03-26 | MTBLS615 | MetaboLights
MetabolomicsSystemic impact of the expression of the mitochondrial alternative oxidase on Drosophila development
Not available
ORGANISM(S): Drosophila melanogaster 
ST002069 | MetabolomicsWorkbench
TranscriptomicsDrosophila brain gene expression with age: mRNA profiling
Gene expression profile in fly brains during development
ORGANISM(S): Drosophila melanogaster 
2011-12-23 | E-GEOD-25007 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila pooled Malpighian tubules vs. whole fly
This is an affymetrix array experiment comparing the transcriptome of the Malpighian tubule (or renal tubule) of 7-day adult Oregon R strain Drosophila melanogaster with matched whole fly samples. It is described in:,Wang, J., Kean, L., Yang, J., Allan, A. K., Davies, S. A., Herzyk, P. and Dow, J. A...
ORGANISM(S): Drosophila melanogaster 
2007-07-06 | E-GEOD-1690 | biostudies-arrayexpress
TranscriptomicsVreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila
In Drosophila, Piwi proteins associate with Piwi-interacting RNAs (piRNAs) and protect the germline genome by silencing mobile genetic elements. This defense system acts in germline and gonadal somatic tissue to preserve germline development. Genetic control for these silencing pathways varies great...
ORGANISM(S): Drosophila melanogaster 
2011-09-28 | E-GEOD-30360 | biostudies-arrayexpress
ProteomicsFly RBPome - Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins
Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins. Posttranscriptional gene regulation by RNA-binding proteins (RBPs) is a dominant force controlli...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-04-26 | PXD002992 | Pride
Fly 
TranscriptomicsGene expression in mitotic tissues of Drosophila larvae without centrosomes or too many centrosomes
Centrosome defects are a common feature of many cancers. Surprisingly, flies can proceed through the majority of development without centrosomes or with amplified centrosomes in most of their cells. It is unclear whether this is because centrosome defects do not cause many problems in Drosophila cel...
ORGANISM(S): Drosophila melanogaster 
2012-08-20 | E-GEOD-35240 | biostudies-arrayexpress
TranscriptomicsConditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration
ATP6AP2 is an essential accessory component of the vacuolar H+ ATPase (V-ATPase) and has been associated with intellectual disabilities (ID) and Parkinsonism. ATP6AP2 has been implicated in several signaling pathways, but little is known about its role in the nervous system. To decipher its function...
ORGANISM(S): Mus musculus 
2015-09-22 | E-GEOD-67541 | biostudies-arrayexpress
TranscriptomicsEarly transcriptional events linked to induction of diapause revealed by RNAseq in larvae of drosophilid fly, Chymomyza costata.
Diapause is an environmentally programmed and hormonally regulated period of dormancy which makes an important part of the life-cycle in many species of invertebrates. In this study, using a RNAseq approach, we focused on very early stages of diapause induction in the larvae of drosophilid fly, Chym...
ORGANISM(S): Chymomyza costata 
2015-08-03 | E-MTAB-3620 | biostudies-arrayexpress
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