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ProteomicsPANNEXIN-1 CHANNEL REGULATES NUCLEAR CONTENT PACKAGING INTO APOPTOTIC BODIES AND THEIR SIZE
Apoptotic bodies (ApoBDs), which are large extracullular vesicles exclusively released by apoptotic cells, possess therapeutically exploitable properties including biomolecule loadability and transferability. However, current limited understanding of ApoBD biology has hindered its exploration for cl...
ORGANISM(S): Homo sapiens (Human) 
2021-04-08 | PXD023988 | Pride
Pannexin 1 Apoptotic bodies Extracellular vesicles Nuclear proteins Dna Cargo sorting 
ProteomicsEfferocytosis of apoptotic bodies drives SARS-CoV-2 infection and macrophage inflammation
SARS-CoV-2 typically utilises host receptor angiotensin-converting enzyme 2 (ACE2) for viral entry. Despite low ACE2 expression, monocyte-derived macrophages, the predominant lung macrophage during severe COVID-19, are often found with SARS-CoV-2 in infected lungs. As macrophage inflammation and cyt...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD077914 | Pride
Covid-19 Apoptotic bodies Macrophage Inflammation Sars-cov-2 Apoptosis Infection Efferocytosis 
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