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Chronic myelogenous leukemia (CML) is a myeloproliferative disorder caused by expression of the chimeric BCR-ABL tyrosine kinase oncogene, resulting from the t(9;22) chromosomal translocation. Imatinib (gleevec, STI-571) is a selective inhibitor of Bcr-Abl activity highly effective in the treatment...
ORGANISM(S): Homo sapiens (Human) 
2018-07-30 | PXD007771 | Pride
Treatment of cultured cells with serum collected from humans on long-term calorie restriction enhances stress resistance in vitro. RNA expression was compared in human foreskin fibroblasts cultured in media supplemented with human sera obtained from: 1) healthy lean and weight-stable volunteers who ...
ORGANISM(S): Homo sapiens 
One of the key aspects of neuronal differentiation is the array of neurotransmitters and neurotransmitter receptors that each neuron possesses. One important goal of developmental neuroscience is to understand how these differentiated properties are established during development. In this paper, we ...
ORGANISM(S): Drosophila melanogaster 
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