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TranscriptomicsAnalysis of cellular responsive nuclear/cytoplasmic mRNA distribution to viral virulence factor and dihydroorotate dehydrogenase (DHODH) inhibition
This SuperSeries is composed of the following subset Series: GSE35112: Genome-wide analysis of gene expression and nuclear/cytoplasmic distribution by compound 1 treatment [293T-M] GSE35113: Genome-wide analysis of gene expression and nuclear/cytoplasmic distribution by compound 1 treatment [293T_NS...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35117 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression by compound 1 treatment [HBEC_6_12hr]
Analysis of cellular response to DHODH inhibition at gene expression level. The NS1 protein of influenza virus is a major virulence factor essential for virus replication as it re-directs the host cell to promote viral protein expression. NS1 inhibits cellular mRNA processing and export, down-regula...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35116 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression by compound 1 treatment [HBEC_3h]
Analysis of cellular response to DHODH inhibition at gene expression level. The NS1 protein of influenza virus is a major virulence factor essential for virus replication as it re-directs the host cell to promote viral protein expression. NS1 inhibits cellular mRNA processing and export, down-regula...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35115 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and nuclear/cytoplasmic distribution by compound 1 treatment [293T-M]
Analysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level. The NS1 protein of influenza virus is a major virulence factor essential for virus replication as it re-directs the host cell to promote viral protein expression. NS1 inhibits cellular mR...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35112 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and nuclear/cytoplasmic distribution by compound 1 treatment [293T_NS1-1]
Analysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level. The NS1 protein of influenza virus is a major virulence factor essential for virus replication as it re-directs the host cell to promote viral protein expression. NS1 inhibits cellular mR...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35113 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and nuclear/cytoplasmic distribution by compound 1 treatment [293T_NS1-2]
Analysis of cellular response to DHODH inhibition at gene expression and nuclear/cytoplasmic distribution level. The NS1 protein of influenza virus is a major virulence factor essential for virus replication as it re-directs the host cell to promote viral protein expression. NS1 inhibits cellular mR...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-35114 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human haptocytes infected with plasmodium reveals circumsporozoite protein promotes the development of the liver stages of the Parasite
The liver stages of malaria sporozoites develop in the hepatocyte cytoplasm inside a parasitophorous vacuole (PV). The circumsporozoite (CS) protein, the major surface protein of sporozoites, traverses the PV membrane and enters the cytoplasm and nucleus of hepatocytes. CS export into the cytoplasm ...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8784 | biostudies-arrayexpress
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