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GenomicsGenome-wide profiling of Zfp335 binding sites in thymocytes
The generation of naM-CM-/ve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have identified a mouse mutant, bloto, that harbors a hypomorphic mutation in the zinc finger protein Zfp335. Mutant blt/blt mice exhibit a naM-...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-58333 | biostudies-arrayexpress
GenomicsGenome wide mapping of NFAT1 binding sites in dendritic cells and of chromatin state in steady and dectin-1 activated dendritic cell line D1
We generated genome-wide chromatin-state maps of mouse dendritic cells in steady and dectin-1 activated with or without NFAT inhibitor FK506. We found the differential H3K4me3 signatures in these cells. This study provides the epigenetic signatures of steady, dectin-1activated with or without NFAT i...
ORGANISM(S): Mus musculus 
2015-01-05 | E-GEOD-59998 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of dectin-1 and NFAT responsive genes in dendritic cells
This study provides the dectin-1 and NFAT responsive genes for 2h and 4h of curdlan treatment. Affymetrix Mouse Gene 1.0ST Arrays were used to profile gene expression in curdlan-stimulated D1 cells (2h or 4h exposure) that had been treated or not with FK506 for the duration of culture. Dendritic cel...
ORGANISM(S): Mus musculus 
2015-02-04 | E-GEOD-59896 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Brassica lines
Transcription profiling of Brassica rapa, Brassica oleracea and Brassica napus I and II The nuclear genomes of the resynthesised B. napus lines should be identical but, as one (B. napus I) involved a cross of B. oleracea onto B. rapa, and the other (B. napus II) involved a cross of B rapa onto B. o...
ORGANISM(S): Brassica rapa 
2010-05-19 | E-GEOD-15915 | biostudies-arrayexpress
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
UnknownGenome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Not available
S-EPMC10790310 | biostudies-literature
UnknownImplantable cardioverter defibrillator and cardiac resynchronization therapy use in New Zealand (ANZACS-QI 33).
Not available
S-EPMC7011834 | biostudies-literature
UnknownQuantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants.
Not available
S-EPMC8896276 | biostudies-literature
UnknownA multi-site, international laboratory study to assess the performance of penicillin susceptibility testing of Staphylococcus aureus.
Not available
S-EPMC10232234 | biostudies-literature
UnknownThe Staphylococcus aureus Network Adaptive Platform Trial Protocol: New Tools for an Old Foe.
Not available
S-EPMC9710697 | biostudies-literature
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