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MetabolomicsUmbilical cord blood metabolome differs in relation to delivery mode, birth order and sex, maternal diet and possibly future allergy development in rural children
Allergy is one of the most common diseases among young children yet all factors that affect development of allergy remain unclear. In a small cohort of 65 children living in the same rural area of south-west Sweden, we have previously found that maternal factors, including prenatal diet, affect chil...
2020-12-18 | MTBLS2017 | MetaboLights
MetabolomicsFecal metabolome alterations in infants at risk of developing allergy during the first year of life

Background: Disturbances in the gut microbiome (GM) during the first year of life may contribute to allergy risk. This period is characterized by rapid microbial colonization, influenced by factors like delivery mode and infant feeding practices. This study investigates changes in key GM taxa and...

2026-06-09 | MTBLS12775 | MetaboLights
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
TranscriptomicsInduction of Interleukin-9-producing Mucosal Mast cells Promotes Susceptibility to IgE-mediated Experimental Food Allergy
Experimental IgE-mediated food allergy depends on intestinal anaphylaxis driven by interleukin (IL)-9. However, the primary cellular source of IL-9 and the mechanisms underlying the susceptibility to food-induced intestinal anaphylaxis remain unclear. Herein, we have reported the identification of m...
ORGANISM(S): Mus musculus 
2015-09-11 | E-GEOD-72921 | biostudies-arrayexpress
MetabolomicsExploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation.

SCOPE: Cow's milk allergy (CMA) is one of the most prevalent food allergies in early childhood, often treated via elimination diets including standard amino acid-based formula or amino acid-based formula supplemented with synbiotics (AAF or AAF-S). This work aimed to assess ...

2024-09-02 | MTBLS8954 | MetaboLights
TranscriptomicsTranscription profiling by array of mouse BALBc strain mesenteric lymph nodes after response to common allergens.
In this study, MLN transcriptome profiling of female BALB/c mice was conducted in order to explore the molecular mechanism(s) of antigen sensitization using three of the most common food allergens; BLG, OVA and PNA. Analysis of cDNA microarray data revealed a complex network of genes that is modulat...
ORGANISM(S): Mus musculus 
2011-05-11 | E-MEXP-2676 | biostudies-arrayexpress
UnknownFood Allergy from Infancy Through Adulthood.
Not available
S-EPMC7899184 | biostudies-literature
GenomicsSamples of murine food allergy model
Samples of murine food allergy model Raw sequence reads
PRJNA853889 | ENA
UnknownThe epidemiology of food allergy in Europe: protocol for a systematic review.
Not available
S-EPMC3762068 | biostudies-literature
UnknownThe acute and long-term management of food allergy: protocol for a rapid systematic review.
Not available
S-EPMC3637062 | biostudies-literature
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