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Comprehensive understanding of venom compositions and in-depth characterisation of the various proteoforms are necessary to aid the development of targeted antivenom strategies. This work utilises an integrated 'omics' and intact mass spectrometry-based approach to profile the diversity within the v...
ORGANISM(S): Naja melanoleuca 
2024-01-03 | PXD045209 | Pride
Three main top-down mass spectrometry methodologies were employed in a proof-of-concept study to characterise selected three finger toxins and phospholipase A2 toxins from the forest cobra (Naja melanoleuca) venom. The novel utility of data-independent acquisition, alternative hybrid ECD-CID fragmen...
ORGANISM(S): Naja melanoleuca 
2024-09-05 | PXD052561 | Pride
African forest cobra venom is a rich source of bioactive compounds such as cytotoxins, which cause tissue necrosis and descending paralysis. However, the venom has also been identified as a potential source of therapeutic agents, including anticancer agents. In this study, we evaluate the anticance...
ORGANISM(S): Cellular Organisms 
Ophiophagus hannah overview
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