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TranscriptomicsGenome wide methylation array analysis in T-ALL
In short: Genome wide promoter DNA methylation profiling of 43 T-ALL samples and 5 T-cell controls (normal bone marrow and stimulated T-cells) . The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Manuscript abst...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-42079 | biostudies-arrayexpress
TranscriptomicsGenome wide gene expression array analysis in T-ALL
In short: The objective with the gene expression array (Illumina HT-12 v.4) analysis of 17 T-ALL samples was to correlate gene expression levels with DNA promoter methylation status. Manuscript Abstract: Background: Treatment of pediatric T-cell acute lymphoblastic leukemia (T-ALL) has improved, but...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-41621 | biostudies-arrayexpress
UnknownTranscriptome sequencing in pediatric acute lymphoblastic leukemia identifies fusion genes associated with distinct DNA methylation profiles.
Not available
S-EPMC5557398 | biostudies-literature
TranscriptomicsDNA methylation adds prognostic value to minimal residual disease status in pediatric T-cell acute lymphoblastic leukemia
Background: Despite increased knowledge about genetic aberrations in pediatric T-cell acute lymphoblastic leukemia (T-ALL), no clinically feasible treatment-stratifying marker exists at diagnosis. Instead patients are enrolled in intensive induction therapies with substantial side effects. In modern...
ORGANISM(S): Homo sapiens 
2016-03-30 | E-GEOD-69954 | biostudies-arrayexpress
UnknownThe mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing.
Not available
S-EPMC4309499 | biostudies-literature
TranscriptomicsCompatible and incompatible infection of potato by nematode Globodera rostochiensis
The cultivar Desirée and the breeding line SW93-1015 were challenged with potato cyst nematodes and transcriptomes analysed after 8h and 48 h.
ORGANISM(S): Solanum tuberosum 
2018-04-02 | E-MTAB-5215 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of MED8 N-truncation mutant, MED18 deletion mutant and MED20 deletion mutant yeast
expression profiles of MED8 N-truncation mutant, MED18 deletion mutant and MED20 deletion mutant against a wild type reference.
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-09 | E-MEXP-1175 | biostudies-arrayexpress
GenomicsThe inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA.
3D-topology of DNA in the cell nucleus provides a level of transcription regulation beyond the sequence of the linear DNA. To study the relationship between transcriptional activity and spatial environment of a gene, we have used allele-specific 4C-technology to produce high-resolution topology maps...
ORGANISM(S): Mus musculus 
2011-06-24 | E-GEOD-29509 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis infected with the bacterium Pseudomonas syringae
The effect of bacterial infection with Pseudomonas syringae on gene expression of Arabidopsis thaliana
ORGANISM(S): Arabidopsis thaliana 
2005-01-01 | E-TIGR-3 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis response to abiotic stresses, heat, cold and salt
The effect of the abiotic stresses, heat, cold and salt on gene expression in Arabidopsis thaliana
ORGANISM(S): Arabidopsis thaliana 
2006-03-21 | E-TIGR-2 | biostudies-arrayexpress
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