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TranscriptomicsAn array based analysis of miRNA expression comparing matched frozen and FFPE human tissue samples
MicroRNAs (miRNAs) are small non-coding RNAs that repress gene expression at the post transcriptional level via an antisense RNA-RNA interaction. Generally, miRNAs derived from snap frozen or fresh samples are used for array based profiling. Since tissues in most pathology departments are available ...
ORGANISM(S): Homo sapiens 
2010-05-17 | E-GEOD-12458 | biostudies-arrayexpress
TranscriptomicsRNAseq Analysis of Formalin-Fixed Paraffin-Embedded Prostate Cancer Tissues
In an effort to identify biomarkers of recurrence, we have performed global RNA-sequencing on 106 formalin-fixed, paraffin-embedded (FFPE) prostatectomy samples from 100 patients at three independent sites, and identified a new set of biomarkers of biochemical recurrence composed of a 24-gene panel....
ORGANISM(S): Homo sapiens 
2014-04-11 | E-GEOD-54460 | biostudies-arrayexpress
TranscriptomicsGene-expression profiles of formalin-fixed, paraffin-embedded human hepatocellular carcinoma
Gene-expression profiles of formalin-fixed, paraffin-embedded human hepatocellular carcinoma tissues obtained at the time of surgical resection. Gene-expression profiling was performed using formalin-fixed, paraffin-embedded hepatocellular carcinoma tissues obtained at the time of surgical resection...
ORGANISM(S): Homo sapiens 
2011-02-17 | E-GEOD-19977 | biostudies-arrayexpress
ProteomicsIdentification of HER2 peptides for quantification in formalin-fixed paraffin-embedded breast cancer tissues
The ability to accurately quantify proteins in formalin-fixed paraffin-embedded (FFPE) tissues using targeted mass spectrometry opens exciting perspectives for biomarker discovery. We have developed and evaluated a selected reaction monitoring (SRM) assay for the human receptor tyrosine-protein kina...
ORGANISM(S): Homo sapiens (Human) 
2015-07-16 | PXD002281 | Pride
Breast cancer Human receptor tyrosine-protein kinase erbb-2 (her2) Human Ltq orbitrap velos Formalin-fixed parrafin-embedded tissues (ffpe) 
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors
This SuperSeries is composed of the following subset Series: GSE25231: Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel GSE25233: Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25234 | biostudies-arrayexpress
TranscriptomicsGene profiling using archival formalin-fixed paraffin-embedded breast cancer specimens can generate informative microarray data: A comparison with matched fresh fine needle aspiration biopsy samples (FFPE samples)
The Formalin-Fixed Paraffin-Embedded (FFPE) samples on selected breast cancer subtypes (ER+/Her2-, ER+/Her2+, ER-/Her2+, and ER-/Her2-) and their paired fresh fine needle aspirated biopsies (FNA) were investigated. The cases represented different subtypes of breast cancers based on their clinical re...
ORGANISM(S): Homo sapiens 
2011-06-22 | E-GEOD-23384 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-10143 | biostudies-arrayexpress
TranscriptomicsDevelopment and Independent Validation of a Prognostic Assay for Stage II Colon Cancer using Formalin Fixed Paraffin Embedded Tissue_Validation Set
Current prognostic factors are poor at identifying patients at risk of disease recurrence following surgery for stage II colon cancer. Here we describe a DNA microarray based prognostic assay using clinically relevant formalin fixed paraffin embedded (FFPE) samples.
ORGANISM(S): Homo sapiens 
2011-11-22 | E-MTAB-864 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, Liver)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-10140 | biostudies-arrayexpress
TranscriptomicsGene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma (Training Set, HCC)
Background: It is a challenge to identify those patients who, after undergoing potentially curative treatments for hepatocellular carcinoma, are at greatest risk of recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predict...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-10141 | biostudies-arrayexpress
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