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ProteomicsPeptide artificial formylation in bottom–up proteomics analyses
The primary objective of this study was to explain excessive formylation rate of peptides that did not come in contact with concentrated formic acid.
ORGANISM(S): Francisella tularensis subsp. holarctica 
2020-06-10 | PXD016597 | Pride
Bottom–up proteomics Formic acid Peptide formylationartificial modifications  bottom–up proteomics  formic acid  peptide formylation Artificial modifications 
ProteomicsFormylation facilitates the reduction of oxidized initiator methionines
Within a cell, protein-bound methionines can be oxidized by reactive oxygen species (ROS) or monooxygenases, and subsequently reduced by methionine sulfoxide reductases (Msrs). Methionine oxidation can result in structural damage or be the basis of functional regulation of enzymes. In addition to pa...
ORGANISM(S): Escherichia coli 
2024-11-06 | PXD048776 | Pride
N-formylation  methionine sulfoxide reductase (msr)  proteomics  mass spectrometry (ms)  methionine oxidation 
UnknownFormylation facilitates the reduction of oxidized initiator methionines.
Not available
S-EPMC11572973 | biostudies-literature
UnknownCatalyst free N-formylation of aromatic and aliphatic amines exploiting reductive formylation of CO2 using NaBH4.
Not available
S-EPMC9037105 | biostudies-literature
TranscriptomicsRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [RNA-seq]
TET enzymes are highly expressed in neural stem cells (NSCs). They oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in a step-wise manner. In this study we have generated NSCs that only lack the Tet formylation and carboxylation ...
ORGANISM(S): Mus musculus 
2025-07-14 | GSE287654 | GEO
Methylation profilingRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [EhmC-seq]
TET enzymes are highly expressed in neural stem cells (NSCs). They oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in a step-wise manner. In this study we have generated NSCs that only lack the Tet formylation and carboxylation ...
ORGANISM(S): Mus musculus 
2025-07-14 | GSE287656 | GEO
Methylation profilingRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [EM-seq]
TET enzymes are highly expressed in neural stem cells (NSCs). They oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in a step-wise manner. In this study we have generated NSCs that only lack the Tet formylation and carboxylation ...
ORGANISM(S): Mus musculus 
2025-07-14 | GSE287655 | GEO
GenomicsRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [CUT&Tag]
TET enzymes are highly expressed in neural stem cells (NSCs). They oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in a step-wise manner. In this study we have generated NSCs that only lack the Tet formylation and carboxylation ...
ORGANISM(S): Mus musculus 
2025-07-14 | GSE298639 | GEO
GenomicsRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [RNA-seq]
Roles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [RNA-seq]
PRJNA1214202 | ENA
GenomicsRoles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [CUT&Tag]
Roles of DNA hydroxymethylation versus DNA formylation and carboxylation in neural stem cells [CUT&Tag]
PRJNA1270073 | ENA
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