Sort   by:  
 Page size 
TranscriptomicsProtective Role of IL-10 in Ozone-induced Pulmonary Inflammation
Background: The mechanisms underlying ozone (O3)-induced pulmonary inflammation remain unclear. Interleukin (IL)-10 is an anti-inflammatory cytokine that is known to inhibit inflammatory mediators. Objectives: The current study investigated the molecular mechanisms underlying IL-10-mediated attenua...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-25095 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of TLR4 pathways in a murine model of chronic pulmonary inflammation and carcinogenesis
Toll like receptor 4 (TLR4), an innate immunity gene, is involved in responses to several pulmonary agonists including endotoxin (LPS; Poltorak et al.,1998), ozone (O3 ,Kleeberger et. al., 2001), Pseudomonas aeruginosa (Faure et al, 2004), and hyperoxia (Zhang et al, 2005). TLR4 appears to partially...
ORGANISM(S): Mus musculus 
2009-12-12 | E-GEOD-8504 | biostudies-arrayexpress
no omics definedTranscription profiling of rat liver and kidney samples performed in 16 different institutions to determine study factors which are key sources of variability. Raw files available as additional archives.
BACKGROUND: The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals w...
ORGANISM(S): Rattus norvegicus 
2008-10-10 | E-TOXM-39 | biostudies-arrayexpress
Sort   by:  
 Page size