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MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
ProteomicsAD+CVD temporal lobe proteome - Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer's disease with cerebrovascular disease
Unbiased discovery-driven quantitative proteomics was performed to profile expression changes and degenerative modifications in the temporal lobe proteome (BA21) of AD+CVD patients compared to normal age-matched controls.
ORGANISM(S): Homo sapiens (Human) 
2016-04-07 | PXD003027 | Pride
Mixed dementia Dpms Dementia Ba21 
MetabolomicsA Murine Model of Maternal Micronutrient Deficiencies and Gut Inflammatory Host-microbe Interactions in the Offspring.

BACKGROUND & AIMS: Micronutrient deficiency (MND) (ie, lack of vitamins and minerals) during pregnancy is a major public health concern. Historically, studies have considered micronutrients in isolation; however, MNDs rarely occur alone. The impact of co-occurring MNDs on pu...

2024-10-18 | MTBLS3476 | MetaboLights
TranscriptomicsBiological Aging and Circadian Mechanisms in Murine Brown Adipose Tissue, Inguinal White Adipose Tissue, and Liver (Jan 2010 dataset)
The circadian profile of the transcriptomes in murine tissues was compared between groups of young and old male mice. The oscillatory phase and absolute expression levels were evaluated as a function of biological age. Distinct differences in multiple pathways were apparent based on biological and c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-25324 | biostudies-arrayexpress
TranscriptomicsBiological Aging and Circadian Mechanisms in Murine Brown Adipose Tissue, Inguinal White Adipose Tissue, and Liver (Nov 2009 dataset)
The circadian profile of the transcriptomes in murine tissues was compared between groups of young and old male mice. The oscillatory phase and absolute expression levels were evaluated as a function of biological age. Distinct differences in multiple pathways were apparent based on biological and c...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-25323 | biostudies-arrayexpress
UnknownParticular CSF sphingolipid patterns identify iNPH and AD patients.
Not available
S-EPMC6133966 | biostudies-literature
UnknownNo difference in ad libitum energy intake in healthy men and women consuming beverages sweetened with fructose, glucose, or high-fructose corn syrup: a randomized trial.
Not available
S-EPMC4658464 | biostudies-literature
UnknownMRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults.
Not available
S-EPMC3466670 | biostudies-literature
TranscriptomicsWeight-reduction by low-fat diet cause differently-expressed circulating microRNAs in obese C57BL/6 mice
To profile the expression of circulating miRNAs in a mouse model of diet-induced obesity (DIO) with subsequent weight-reduction with low-fat diet (LFD), eighteen C57BL/6 male mice were grouped into three subgroups as: (1) Control: the mice fed with the standard AIN-76A (fat: 11.5 kcal%) diet for 12 ...
ORGANISM(S): Mus musculus 
2014-09-03 | E-GEOD-61005 | biostudies-arrayexpress
TranscriptomicsMolecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disorder characterized by ptosis, dysphagia and proximal limb weakness. Autosomal-dominant OPMD is caused by a short (GCG)8–13 expansions within the first exon of the poly(A)-binding protein nuclear 1 gene (PABPN1), leading to an expanded p...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-26604 | biostudies-arrayexpress
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