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ProteomicsA viral pan-end RNA element and host complex define a SARS-CoV-2 regulon
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer genomic RNA, all bearing identical termini with poorly understood roles in regulating viral gene expression. Insulin and interferon...
ORGANISM(S): Homo sapiens (Human) 
2023-06-12 | PXD042148 | Pride
Sars-cov-2  covid-19  translational control  rna element  rna-binding protein  eprs1  aminoacyl-trna synthetase  multi-trna synthetase complex  post-transcriptional regulon  3’ untranslated region  obesity  insulin  interferon-gamma  spike protein  subgenomic rna  programmed ribosomal frameshifting  spear element  orf10  3’end  sars-cov-2 replicon  ppmo 
TranscriptomicsTransient treatment with epigenetic modifiers yields stable neuroblastoma stem cells resembling aggressive large-cell neuroblastomas
Cancer stem cells (CSCs) are plastic in nature, a characteristic that hampers cancer therapeutics. Neuroblastoma (NB) is a pediatric tumor of neural crest origin, and half of the cases are highly aggressive. By treating NB cell lines (SKNAS, SKNBE(2)C, CHP134, SY5Y) with epigenetic modifiers for a...
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-44537 | biostudies-arrayexpress
UnknownIL-17-induced HIF1α drives resistance to anti-PD-L1 via fibroblast-mediated immune exclusion.
Not available
S-EPMC8996325 | biostudies-literature
UnknownA Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines.
Not available
S-EPMC5399443 | biostudies-literature
UnknownGBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians.
Not available
S-EPMC12164542 | biostudies-literature
UnknownCommon and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.
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S-EPMC3724194 | biostudies-literature
UnknownCD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Not available
S-EPMC3703870 | biostudies-literature
UnknownCommon breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.
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S-EPMC3326552 | biostudies-literature
UnknownQuantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.
Not available
S-EPMC3959810 | biostudies-literature
UnknownPathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Not available
S-EPMC4129409 | biostudies-literature
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