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TranscriptomicsTranscriptome In Vivo Analysis (TIVA) of spatially defined single cells in intact live mouse and human brain tissue
Transcriptome profiling is an indispensable tool in advancing the understanding of single cell biology, but depends upon methods capable of isolating mRNA at the spatial resolution of a single cell. Current capture methods lack sufficient spatial resolution to isolate mRNA from individual in vivo re...
ORGANISM(S): Mus musculus 
2014-01-12 | E-GEOD-52525 | biostudies-arrayexpress
GenomicsWhole Genome Association Study of Bipolar Disorder

The goal of the project is to identify genes that make individuals more susceptible to bipolar disorder (manic depressive illness) and to better understand the brain pathways involved in the disease.

Dataset versioning

  • Version 1: European-American (EA) ancestr...
phs000017.v3.p1 | EGA
GenomicsChromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants (ChIP-seq)
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome pro- filing in human pancreatic islets. Integra...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-51311 | biostudies-arrayexpress
TranscriptomicsChromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants (RNA-seq)
Chromatin-based functional genomic analyses and genomewide association studies (GWASs) together implicate enhancers as critical elements influencing gene expression and risk for common diseases. Here, we performed systematic chromatin and transcriptome profiling in human pancreatic islets. Integrate...
ORGANISM(S): Homo sapiens 
2013-11-08 | E-GEOD-51310 | biostudies-arrayexpress
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