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GenomicsDeep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer
Our understanding of genomic heterogeneity in lung cancer is largely based on the analysis of early-stage surgical specimens. Here we used endoscopic sampling of paired primary and intrathoracic metastatic tumors from 11 lung cancer patients to map genomic heterogeneity inoperable lung cancer with d...
EGAS00001003830 | EGA
GenomicsGarvan Institute of Medical Research
Data Access Committee EGAC00001001300
EGAC00001001300 | EGA
TranscriptomicsRNAi profiling of mouse loss of function mutant using in vivo screening identifies regulators of actin dynamics as key determinants of lymphoma progression
Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. U...
ORGANISM(S): Mus musculus 
2009-09-23 | E-GEOD-16090 | biostudies-arrayexpress
Genomics5b85420b-44cf-4d0a-9fa8-4930e698bc25 - samples
Deep WGS (germline and 2-5 tumour regions) was performed on 20 patients: 13 lung adenocarcinoma, 5 squamous cell carcinoma, 2 small-cell lung cancers. A total of 68 BAM files are provided, where tumours were sequenced to 60x or 150x depth.
EGAD00001005287 | EGA
ProteomicsMotif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity
Plant cell surface pattern recognition receptors (PRRs) perceive non- or altered-self elicitors to induce immune responses. PRRs relay information across the plasma membrane and trigger downstream signaling via receptor-like cytoplasmic kinases (RLCKs) such as BOTRYTIS-INDUCED KINASE 1 (BIK1). BIK1 ...
ORGANISM(S): Arabidopsis Thaliana 
PXD066643 | panorama
UnknownMedicare Beneficiaries With Self-Reported Functional Hearing Difficulty Have Unmet Health Care Needs.
Not available
S-EPMC8323057 | biostudies-literature
MetabolomicsGNPS - Bacterial Bile Acid Amidates (BBAAs) data set
Data acquired for conjugated bile acids with amino acids analysis of human fecal samples by targeted LC-MS. These samples are a part of a study investigating a new BSH function as an amine N-acyl transferase that conjugates amines to form bacterial bile acid amidates (BBAAs).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-18 | MSV000093144 | GNPS
TranscriptomicsTranscription profiling of liver from Dahl salt sensitive (SS) rats and SS9BN consomic rats during hypoxia treatment
Examination of gene expression associated with hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SS9BN) rat strain. SS9BN rats are derived from introgression of chromosome 9 from BN rats into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-126 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from Dahl salt sensitive (SS) rats and SS9BN consomic rats during hypoxia treatment
Examination of gene expression associated with hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SS9BN) rat strain. SS9BN rats are derived from introgression of chromosome 9 from BN rats into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-127 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from Dahl salt sensitive (SS) rats and SS11BN consomic rats during hypoxia treatment
Examination of gene expression changes during hypoxia of the Dahl salt sensative (SS) rat and SS11BN consomic rat. SS11BN rats are derived from introgression of chromosome 11 from Brown Norway (BN) rat into the SS genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-116 | biostudies-arrayexpress
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