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MetabolomicsLarge neutral amino acid levels tune perinatal neuronal excitability and survival
Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically-...
2023-03-28 | MTBLS6578 | MetaboLights
ProteomicsHB digestion with Pepsin and Napsin
HB digestion with Pepsin and Napsin t=20, 60 and 120 min Analysis by nanoLC-ESI-iTRAP-OrbiTrap
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-10 | MSV000087400 | MassIVE
ProteomicsThe calcium-permeable channel OSCA1.3 regulates plant stomatal immunity
Perception of biotic and abiotic stresses often leads to stomatal closure in plants. Rapid influx of calcium ions (Ca2+) across the plasma membrane plays an important role in this response, but the identity of Ca2+ channels involved has remained elusive. Here, we report that the Arabidopsis thaliana...
ORGANISM(S): Arabidopsis Thaliana 
2020-09-11 | PXD020852 | panorama
GenomicsTwo distinct auto-regulatory loops operate at the Pu.1 locus in B cells and myeloid cells
The transcription factor PU.1 occupies a central role in controlling myeloid and early B cell development and its correct lineage-specific expression is critical for the differentiation choice of hematopoietic progenitors. However, little is known of how this tissue-specific pattern is established. ...
ORGANISM(S): Mus musculus 
2011-02-21 | E-GEOD-26550 | biostudies-arrayexpress
TranscriptomicsMultiplex Single Cell Profiling of Chromatin Accessibility by Combinatorial Cellular Indexing [RNA-seq]
Technical advances have enabled the collection of genome and transcriptome data sets with single-cell resolution. However, single-cell characterization of the epigenome has remained challenging. Furthermore, because cells must be physically separated prior to biochemical processing, conventional sin...
ORGANISM(S): Homo sapiens 
2015-05-07 | E-GEOD-68102 | biostudies-arrayexpress
UnknownThe Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type-III effector
Not available
S-SCDT-10_15252-EMBJ_2020107257 | biostudies-other
Unknowncest-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants
Not available
S-SCDT-EMBOR-2021-52606V1 | biostudies-other
GenomicsPS
Psoriasis cases as part of WTCCC2 phase 2
EGAD00010000124 | EGA
GenomicsGenome wide association scan in psoriasis
To identify novel susceptibility loci for psoriasis, we undertook a genome-wide association scan of of 594,224 SNPs in 2,622 individuals with psoriasis and 5,667 controls.
EGAS00000000108 | EGA
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
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