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TranscriptomicsTranscription profiling of Methanosarcina mazei Goe1 in response to bismuth nitrate.
Pattern of gene expression of M. mazei in response to 10 uM bismuth nitrate was analyzed relative to gene expression pattern of M. mazei grown in the presence of 30 uM potassium nitrate (control cultures). Therefore, five pre-cultures of M. mazei was grown to mid-exponential growth-phase. Then, the ...
ORGANISM(S): Methanosarcina mazei 
2011-10-01 | E-MTAB-787 | biostudies-arrayexpress
TranscriptomicsMycorrhizal Metabolome: L. bicolor :: P. trichocapra
Mycorrhizae, symbiotic interactions between soil fungi and tree roots, are ubiquitous in terrestrial ecosystems. The fungi contribute phosphorous, nitrogen and mobilized nutrients from organic matter in the soil and in return the fungus receives photosynthetically-derived carbohydrates. This union...
ORGANISM(S): Populus tremuloides 
2011-03-25 | E-GEOD-28157 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells before and after exercise
Analysis of peripheral blood mononuclear cells (PBMCs) separated from whole blood of healthy male subjects; - prior to onset of exercise; - immediately following the end of exercise and; - immediately following 1 hour of recovery from exercise. To reduce individual variation and other confounding ev...
ORGANISM(S): Homo sapiens 
2007-07-21 | E-GEOD-1140 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chromic myeloid leukemia (CML) patients treated second-line with imatinib after failure of an interferon-alpha based therapy to identify genes with predictive value for primary cytogenetic outcome to imatinib
Identification of genes in CML patients with predictive value for their primary cytogenetic outcome to imatinib. All samples analyzed were taken just before the start of imatinib treatment. Leukemic patients were treated second-line with imatinib after failure of an interferon-alpha based therapy (f...
ORGANISM(S): Homo sapiens 
2006-05-31 | E-MEXP-433 | biostudies-arrayexpress
MetabolomicsAMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism.
Dendritic cell (DC) activation and function are underpinned by profound changes in cellular metabolism. Several studies indicate that the ability of DCs to promote tolerance is dependent on catabolic metabolism. Yet the contribution of AMP-activated kinase (AMPK), a central energy sensor promoting c...
2024-08-16 | MTBLS10647 | MetaboLights
MetabolomicsNon-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1500 Da) were measured in urine collected from 469 lung cancer patients and 536 population controls using u...
2014-05-06 | MTBLS28 | MetaboLights
no omics definedTranscription profiling of human hippocampi from epilepsy patients with and without hippocampal sclerosis and autopsy controls
Genome wide gene expression was compared between nonHS, HS temporal lobe epilepsy patients (TLE) and autopsy control hippocampi in a 3-way analysis. In many TLE patients the hippocampus is subject to massive neuronal damage, gliosis and hippocampal sclerosis (HS), while in others there is no apparen...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-MEXP-744 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis for leaves of Arabidopsis thaliana Col-0 plants fumigated with nitrogen dioxide (treatment) or air (control)
Four-week-old Arabidopsis thaliana (Col-0) plants were fumigated for 1 h with 10 parts per million (ppm) nitrogen dioxide (NO2) to analyse leaf transcriptome changes induced by this air pollutant relative to air-fumigated control plants.
ORGANISM(S): Arabidopsis thaliana 
2018-08-10 | E-MTAB-6522 | biostudies-arrayexpress
GenomicsGenome-Wide Association Study of Schizophrenia

The goal of the study is to find susceptibility genes for schizophrenia.

Dataset versioning

  • Version 1: European-American (EA) ancestry only
  • Version 2: Version 1 plus African-American (AA) ancestry

Consent groups and p...

phs000021.v3.p2 | EGA
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
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