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TranscriptomicsComparison of gene expression profiles between human and mouse monocyte subsets [mouse data]
Human and mouse blood each contain two monocyte subsets. Here, we investigated the extent of their similarity using a microarray approach. Approximately 300 genes in human and 550 genes in mouse were differentially expressed between subsets. More than 130 of these gene expression differences were co...
ORGANISM(S): Mus musculus 
2009-12-03 | E-GEOD-17256 | biostudies-arrayexpress
TranscriptomicsTranscription profling of human neuroblastoma samples to construct, validate and evalute a gene expression based classification of outcome of treatment
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2009-02-17 | E-TABM-38 | biostudies-arrayexpress
TranscriptomicsGenome-scale RNAi profiling of cell division in human tissue culture cells
Cell division is a fundamental process for multicellula organisation. Here we report a genome-scale RNAi screen in HeLa cells designed to identify human genes important for cell division. We utilized a library of endoribonuclease-prepared siRNAs (esiRNAs) for gene-silencing and used DNA content an...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-9176 | biostudies-arrayexpress
ProteomicsMass spectrometry-based draft of the mouse proteome
Quantitative draft map of the proteomes of 41 healthy tissues of the animal model Mus musculus and a panel of 66 murine pancreatic ductal adenocarcinoma cell lines and. Our in-depth analysis provides evidence for proteins encoded by >16,000 genes (~76% of the total annotated protein-coding genes), w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-07-09 | MSV000089856 | MassIVE
ProteomicsMitochondrial damage drives T-cell immunometabolic paralysis after major surgery
Cytotoxic T cell (CTL) dysfunction is a key feature of immune paralysis following major surgery, significantly increasing the risk of severe nosocomial infections and contributing to elevated mortality in critically ill patients. The pathomechanisms of CTL dysfunction remain unclear. We report that ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-02-04 | MSV000097035 | MassIVE
GenomicsEGAS00000000046-ega-20110530 - samples
ICGC Germany PedBrain Medulloblastoma Pilot_2_LM
EGAD00001000027 | EGA
GenomicsLinking genes, genomic instability and molecular subgroups in medulloblastoma
Brain tumors are the second most common pediatric cancer and carry the highest mortality rates in this age group. Medulloblastoma is the most frequent malignant brain tumor of childhood. Recent studies indicate that medulloblastoma comprises at least four sub-entities (SHH-signaling, WNT-signali...
EGAS00001000085 | EGA
MetabolomicsSARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals
Viruses manipulate cellular metabolism and macromolecule recycling processes like autophagy. Dysregulated metabolism might lead to excessive inflammatory and autoimmune responses as observed in severe and long COVID-19 patients. Here we show that SARS-CoV-2 modulates cellular metabolism and reduces ...
2021-06-11 | MTBLS2840 | MetaboLights
UnknownRivaroxaban vs Vitamin K Antagonist in Patients With Atrial Fibrillation and Advanced Chronic Kidney Disease.
Not available
S-EPMC11198259 | biostudies-literature
UnknownCirculating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study.
Not available
S-EPMC4605674 | biostudies-literature
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