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GenomicsThe SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators - ChIP-seq
The heptarepeats of the C-terminal domain of Pol II are extensively modified throughout the transcription cycle. The CTD coordinates RNA synthesis and processing by recruiting transcription regulation factors as well as RNA capping, splicing and 3’end processing factors. The SPOC domain of PHF3 was ...
ORGANISM(S): Homo sapiens 
2023-02-22 | E-MTAB-11506 | biostudies-arrayexpress
TranscriptomicsIdentification of the alternative sigma factor SigX regulon and its implications for Pseudomonas aeruginosa pathogenicity
We analyzed a deletion mutant of the ECF M-OM-^C factor SigX and applied mRNA profiling to define the SigX dependent regulon in P. aeruginosa in response to low osmolarity medium conditions. Furthermore, the combination of transcriptional data with chromatin immunoprecipitation (ChIP) followed by hi...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2013-11-11 | E-GEOD-50937 | biostudies-arrayexpress
UnknownA "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis.
Not available
S-EPMC3655974 | biostudies-literature
TranscriptomicsAlterations in cardiac DNA methylation in human dilated cardiomyopathy
This project analyzes genome-wide cardiac DNA methylation in patients with idopathic DCM and control individuals Given are datafiles from n = 8 controls (patients after Htx) and n = 9 patients with idopathic DCM. The datasets have been normalized together with other beadchip files not subject to thi...
ORGANISM(S): Homo sapiens 
2012-12-18 | E-GEOD-42510 | biostudies-arrayexpress
UnknownGenome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.
Not available
S-EPMC11824687 | biostudies-literature
UnknownEpidemiology, ventilation management and outcomes of COVID-19 ARDS patients versus patients with ARDS due to pneumonia in the Pre-COVID era.
Not available
S-EPMC11330602 | biostudies-literature
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