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Solute carriers belong to the biggest group of transporters in the human genome, but more knowledge is needed in order to fully understand their function and possible role as therapeutic targets. SLC38 is a family of amino acid transporters, commonly referred to as SNATs, consisting of 11 members. T...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD039572 | Pride
Samples-WT Basal condition primary cortex cells; WT B27 Starved-Primary cortex cells starved overnight without B27 supplement media. WT AA Starved-Primary cortex cell starved without amino acid for 2 hours. WT AA Refed-Primary cortex cell refed for 1 hour after amino acid starvation. KO Basal-SLC38 ...
ORGANISM(S): Mus musculus 
Half a brain hemisphere from adult male mice with Slc18b1 knocked out globally, was compared to brain from control littermates.
ORGANISM(S): Mus musculus 
FTO gene variants show the strongest association to obesity so far, but the role of the gene in obesity remains unclear. The FTO protein is a demethylation enzyme, which suggests that the link to obesity could be mediated through epigenetic changes. Herein, we determine the genome wide DNA methylati...
ORGANISM(S): Homo sapiens 
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