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Copy number alterations in a matched pair of benign epithelial and prostate cancer cell lines derived from the same patient were assessed using array-based comparative genomic hybridisation (aCGH). the cancer cell line showed a gain of chromosome 7, deletion of chromosome 8, gains and losses in chro...
ORGANISM(S): Homo sapiens 
Background and Purpose: Adrenal glucocorticoids (GC) increase acutely after myocardial infarction (MI) and thereafter tissue levels are maintained selectively within cells expressing the enzyme 11ßHydroxysteroid Dehydrogenase type 1 (11ßHSD1) that regenerates active GC from circulating metabolites. ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-01-15 | PXD055401 | Pride
A WTCCC2 project genome-wide study for pharmacogenomic response to statins (PR) in individuals from Scotland.
Bile acids (BAs), via the nuclear receptor FXR, regulate a complex transcriptional program to maintain fat, glucose, and protein metabolism. The mTORC1 signalling pathway integrates diverse nutrient/hormonal signals into FXR-related metabolic outputs, raising the question whether these transcription...
ORGANISM(S): Homo sapiens 
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