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TranscriptomicssiRNA knock down of RIP140 in the presence of retinoic acid vs controls to investigate the role of RIP140 in retinoid mediated signaling
Cell-and context-specific activities of nuclear receptors may in part be due to distinct coregulator complexes recruited to distinct subsets of target genes. RIP140 (also called NRIP1) is a ligand-dependent corepressor that is inducible with retinoic acid (RA). We have shown previously that silen...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-7500 | biostudies-arrayexpress
UnknownManagement of Multi-Casualty Incidents in Mountain Rescue: Evidence-Based Guidelines of the International Commission for Mountain Emergency Medicine (ICAR MEDCOM).
Not available
S-EPMC6014052 | biostudies-literature
TranscriptomicsDm Snail Affymetrix ChIP
Genomewide mapping of D. melanogaster Snail protein binding during embryonic development at 2-4 hrs after egg-laying. Two independent repeats were assayed and preimmune-serum was used as a control. The enriched DNA was hybridized to high density Affymetrix GeneChip Drosophila Tiling 1.0R array
ORGANISM(S): Drosophila melanogaster 
2014-01-10 | E-MTAB-1589 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human NT2 cell line treated with DMSO vs. retinoic acid
NT2 cells were treated with DMSO (control) or 10uM Retinoic Acid (RA). Total RNA was isolated using TriReagent, and subsequent cleanup with RNeasy columns (Qiagen) according to the manufacturer's directions. Hybridizations were performed according to Affymetrix guidelines using the Human HG-U133A ...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2448 | biostudies-arrayexpress
TranscriptomicsPhotoreceptor precursors derived from 3D cultures of embryonic stem cells mature and integrate in degenerate retina
To isolate photoreceptor precursors fit for transplantation, we adapted a 3D differentiation protocol that generates neuroretina from mouse ES cells. We used an adeno-associated viral vector (pseudotype2/9)carrying a GFP reporter under the control of a Rhodopsin promoter (AAV2/9.Rhop.GFP)to select r...
ORGANISM(S): Mus musculus 
2013-07-17 | E-MEXP-3921 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Caenorhabditis elegans whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells.
Tissue specific microarray data is obtained by generating a whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells (Roy et al. 2002). Different lines were compared: SV911 (control), SV912 (CY...
ORGANISM(S): Caenorhabditis elegans 
2011-11-25 | E-TABM-886 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of ataxin-null (Atxn-null) vs. wild type mice to investigate spinocerebellar ataxia type 1 (SCA1)
Ataxin 1 (Atxn1) is a protein of unknown function associated with cerebellar neurodegeneration in spinocerebellar ataxia type 1 (SCA1). SCA1 is caused by an expanded polyglutamine within Atxn1 by gain-of-function mechanisms. Lack of Atxn1 in mice triggers motor deficits in the absence of neurodegene...
ORGANISM(S): Mus musculus 
2006-12-01 | E-MEXP-886 | biostudies-arrayexpress
UnknownEnhanced postoperative surveillance versus standard of care to reduce mortality among adult surgical patients in Africa (ASOS-2): a cluster-randomised controlled trial.
Not available
S-EPMC8440223 | biostudies-literature
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