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TranscriptomicsHigh-resolution view of the yeast meiotic program revealed by ribosome profiling
Meiosis is a complex developmental process that generates haploid cells from diploid progenitors. We measured mRNA abundance and protein production through yeast sporulation and found strong temporal control for most genes, achieved through both mRNA levels and translational regulation. Monitoring t...
ORGANISM(S): Saccharomyces cerevisiae 
2012-01-06 | E-GEOD-34082 | biostudies-arrayexpress
GenomicsHigh-Resolution Nucleosome Mapping Reveals Transcription-Dependent Promoter Packaging
Genome-wide mapping of nucleosomes has revealed a great deal about the relationships between chromatin structure and control of gene expression, and has led to mechanistic hypotheses regarding the rules by which chromatin structure is established. High-throughput sequencing has recently become the t...
ORGANISM(S): Saccharomyces cerevisiae 
2009-10-15 | E-GEOD-18530 | biostudies-arrayexpress
UnknownCondition-specific genetic interaction maps reveal crosstalk between the cAMP/PKA and the HOG MAPK pathways in the activation of the general stress response.
Not available
S-EPMC4631200 | biostudies-literature
TranscriptomicsReplication and active demethylation represent partially overlapping mechanisms for erasure of H3K4me3 in budding yeast
Histone modifications affect DNA-templated processes ranging from transcription to genomic replication. In this study, we examine the cell cycle dynamics of the trimethylated form of histone H3 lysine 4 (H3K4me3), a mark of active chromatin that is viewed as â??long-livedâ?? [1], and that is involve...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14565 | biostudies-arrayexpress
UnknownImmunogenetics. Chromatin state dynamics during blood formation.
Not available
S-EPMC4412442 | biostudies-literature
TranscriptomicsStructure and Function of a Transcriptional Network Activated by Hog1
Cells regulate gene expression using a complex network of signaling pathways, transcription factors and promoters. To gain insight into the structure and function of these networks we analyzed gene expression in single and multiple mutant strains to build a quantitative model of the Hog1 MAPK-depen...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12270 | biostudies-arrayexpress
TranscriptomicsNucleosome occupancy
Chromatin plays roles in processes governed by different time scales. To assay the dynamic behaviour of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested S. cerevisiae at single-nucleosome resolution over 4% of the genome, and over the entire geno...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-GEOD-6668 | biostudies-arrayexpress
UnknownModular Drug-Loaded Nanocapsules with Metal Dome Layers as a Platform for Obtaining Synergistic Therapeutic Biological Activities.
Not available
S-EPMC10623511 | biostudies-literature
UnknownElucidating Combinatorial Chromatin States at Single-Nucleosome Resolution.
Not available
S-EPMC5031555 | biostudies-literature
GenomicsPatterns and mechanisms of ancestral histone protein inheritance in budding yeast
It is widely believed that chromatin, the nucleoprotein packaging state of eukaryotic genomes, can carry epigenetic information to propagate gene expression patterns in replicating cells. However, inheritance of genomic packaging status is subject to mechanistic challenges that do not confront the i...
ORGANISM(S): Saccharomyces cerevisiae 
2011-10-06 | E-GEOD-28269 | biostudies-arrayexpress
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