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TranscriptomicsGene Expression of ApoE Null and ApoE Null/RAGE Diabetic and Non-diabetic Mice
The multi-ligand Receptor for AGE (RAGE) contributes to atherosclerosis in apolipoprotein (ApoE) null mice in both the non-diabetic and diabetic states. Previous studies using soluble RAGE, the extracellular ligand-binding domain of RAGE, or homozygous RAGE null mice showed that blockade or deletion...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-15729 | biostudies-arrayexpress
TranscriptomicsDeactivation of Hepatic Stellate Cells during Liver Fibrosis Resolution in Mice
Gene expression of mouse hepatic stellate cells was characterized under the following conditions: Quiescent (isolated from normal mouse liver) and reverted (isolated from mouse liver treated with 4 injections of carbontetrachloride followed by 45 day rest period) Affymetrix Mouse 1.0ST gene express...
ORGANISM(S): Mus musculus 
2014-05-05 | E-GEOD-38648 | biostudies-arrayexpress
TranscriptomicsAger (Rage) and Myd88 deletion in resected mouse livers
The effect of resection of mouse livers on survival serve as a model for the effect of resection of human livers, which are performed for both the purposes of removing sick tissue and for transplanting healthy tissue. When less than 70% of a mouse liver is resected, the mouse usually lives. However,...
ORGANISM(S): Mus musculus 
2012-06-25 | E-GEOD-22873 | biostudies-arrayexpress
TranscriptomicsEffect of transgenic human IL8 on gene expression in mouse colon cancer tumors
mRNA expression in colon cancer tumores of CBA/C57BL/6 transgenic mice bearing a BAC which contains the human IL8 gene and promoter was compared to that of CBA/C57BL/6 controls. A. CBA/C57BL/6 mice controls (n=3) B. human IL8 transgenic CBA/C57BL/6 mice (n=3).
ORGANISM(S): Mus musculus 
2013-01-11 | E-GEOD-39273 | biostudies-arrayexpress
GenomicsTranscription factor ChIP-seq in expanded human hematopoietic stem and progenitor cells
While many individual transcription factors are known to regulate hematopoietic differentiation, major aspects of the global architecture of hematopoiesis remain unknown. Here, we profiled gene expression in 38 distinct purified populations of human hematopoietic cells and used probabilistic models ...
ORGANISM(S): Homo sapiens 
2011-01-26 | E-GEOD-26014 | biostudies-arrayexpress
TranscriptomicsDifferential expression of mouse Grem1+ Vs. Grem1- bone-marrow cells
The gene expression of bone marrow cells of mice enriched for Gremlin1 vs control was measured (n=3). It is not known if endogenous adult mesenchymal stem cells (MSCs) exist.Following culture,perisinusoidal mesenchymal cells can clonally recapitulate the skeletal microenvironment, but this fails to ...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-57729 | biostudies-arrayexpress
UnknownNovel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways.
Not available
S-EPMC6235897 | biostudies-literature
UnknownA global metagenomic map of urban microbiomes and antimicrobial resistance.
Not available
S-EPMC8238498 | biostudies-literature
UnknownFunctional status at 18 months of age as a predictor of childhood disability after neonatal hypoxic-ischemic encephalopathy.
Not available
S-EPMC4324462 | biostudies-literature
UnknownGenome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.
Not available
S-EPMC7255059 | biostudies-literature
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