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ProteomicsComprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories
In this study, we evaluated the feasibility of proteomics and phosphoproteomics on formalin-fixed paraffin-embedded (FFPE) lung tissue for protein extraction protocols, quantification methods, pre-analytics, and sample size. First, we compared three protocols for the extraction of proteins from FFPE...
ORGANISM(S): Homo sapiens (Human) 
2021-05-05 | PXD024800 | Pride
Proteomics Ffpe Nsclc 
ProteomicsUbiquitin-Proteasome System Dyeregulation in Alzheimer's Disease Impacts Protein Abundance.
Alzheimer’s disease is a relentlessly progressive, fatal neurodegenerative disorder associated with widespread aberrant proteomic changes. The full extent of protein dysfunctions in AD and their impact on cellular physiology remains unknown. Here, we used plexDIA, a proteomic profiling approach t...
ORGANISM(S): Homo sapiens (Human) 
2025-05-27 | PXD064265 | Pride
Alzheimer's disease Human 
Genomicsena-DATASET-IfGH-11-05-2017-08:36:08:072-67 - samples
Clinical and genetic information of an individual with RVOT-VT and a KCNK2 (TREK1) gene mutation obtained after whole exome sequencing.
EGAD00001003328 | EGA
GenomicsWhole exome sequencing in RVOT patients
In a patient with right ventricular outflow tract (RVOT) tachycardia we identified a heterozygous point mutation in the selectivity filter of the stretch-activated K2P potassium channel TREK-1 (KCNK2 or K2P2.1). This mutation introduces abnormal sodium permeability to TREK-1 In addition, mutant chan...
EGAS00001002319 | EGA
GenomicsWhole exome sequencing in cardiovascular patients
Data Access Committee EGAC00001000621
EGAC00001000621 | EGA
ProteomicsDifferences in proteomic microglia from male and female brains
To determine the contribution at protein levels to the steady state of the cells in different sexes, we estimated the relative amounts of the microglia cells by mass spectrometry-based proteomics approach and further label-free quantification analysis (LFQ). We analysed the differences of protein ab...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-11-02 | MSV000081661 | MassIVE
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