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MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownThe Impact of Frequency Scale on the Response Sensitivity and Reliability of Cortical Neurons to 1/fβ Input Signals.
Not available
S-EPMC6637762 | biostudies-literature
UnknownNucleophilic cleavage of C-F bonds by Bronsted base for rapid synthesis of fluorophosphate materials.
Not available
S-EPMC11841365 | biostudies-literature
UnknownFangchinoline attenuates cardiac dysfunction in rats with endotoxemia via the inhibition of ERK1/2 and NF-κB p65 phosphorylation.
Not available
S-EPMC7576032 | biostudies-literature
ProteomicsGeneral proteomics and lactylation-modified proteomics were used to detect 5 cases of prostate cancer tissues and 5 cases of benign prostatic hyperplasia tissues
Proteomic sequencing was performed on 5 prostate cancer patient tissues and 5 benign prostatic hyperplasia patient tissues collected from Beijing Tongren Hospital Affiliated to Capital Medical University. Differential genes related to the prognosis of prostate cancer were identified, and enrichment ...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD066054 | Pride
Human  pca  bph  lactylation 
TranscriptomicsMolecular dissection of drought tolerance mechanisms in rice by comparative deep transcriptome sequencing
To dissect the molecular mechanisms underlying drought tolerance (DT) in rice, transcriptome differences of a DT introgression line H471, the DT donor P28 and the drought sensitive recurrent parent HHZ under drought stress were investigated using deep transcriptome sequencing. Results revealed a dif...
ORGANISM(S): Oryza sativa 
2014-12-30 | E-GEOD-57950 | biostudies-arrayexpress
UnknownRegulation of energy metabolism by combination therapy attenuates cardiac metabolic remodeling in heart failure.
Not available
S-EPMC7645995 | biostudies-literature
UnknownAmphiphilic Cationic Peptide-Coated PHA Nanosphere as an Efficient Vector for Multiple-Drug Delivery.
Not available
S-EPMC9457696 | biostudies-literature
TranscriptomicsGenome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples
Comparison between in vitro transcription- and cDNA-mediated annealing, selection and ligation (DASL)-based assays on brain-specific reference RNA, and postmortem frozen and formalin fixed brain tissue from autistic and control cases. Investigation of data preprocessing techniques for DASL-assayed ...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-28475 | biostudies-arrayexpress
MetabolomicsComparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study
Background: Autism spectrum disorder (ASD) is defined as a pervasive developmental disorder which is caused by genetic and environmental risk factors. Besides the core behavioral symptoms, accumulated results indicate children with ASD also share some metabolic abnormalities. Objectives:
2022-03-02 | MTBLS2421 | MetaboLights
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