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UnknownValidation of the 12-gene colon cancer recurrence score in NSABP C-07 as a predictor of recurrence in patients with stage II and III colon cancer treated with fluorouracil and leucovorin (FU/LV) and FU/LV plus oxaliplatin.
Not available
S-EPMC3871512 | biostudies-literature
TranscriptomicsIdentification of a microRNA expression signature for radiochemosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g
Purpose: Preoperative 5-fluorouracil (5-FU) based radiochemotherapy (RCT) represents the standard treatment for locally advanced rectal cancer. Both, tumor response and progression vary considerably. MicroRNAs represent master regulators of gene expression, and may therefore contribute to this heter...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-40976 | biostudies-arrayexpress
TranscriptomicsMIcroRNA expression profiling of chemotherapy resistant esophageal adeno- and squamous cell carcinoma cell lines
Chemotherapy resistance adversely impacts the treatment of some individuals with esophageal cancer. Identifying chemotherapy resistance might help tailor clinical treatments. In this study the impact of microRNAs on chemotherapy resistance in esophageal cancer was investigated. We used microarrays t...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-50224 | biostudies-arrayexpress
UnknownCombination of Knoevenagel Polycondensation and Water-Assisted Dynamic Michael-Addition-Elimination for the Synthesis of Vinylene-Linked 2D Covalent Organic Frameworks.
Not available
S-EPMC9401016 | biostudies-literature
Proteomics4-Oxo-2-nonenal Adductions in Cells
4-Oxo-2-nonenal (ONE) derived from lipid peroxidation modifies nucleophiles and transduces redox signaling by its reactions with proteins. However, the molecular interactions between ONE and complex proteomes and their dynamics in situ remain largely unknown. Here we de-scribe a quantitative chemopr...
ORGANISM(S): Homo sapiens (Human) 
2017-08-25 | PXD007149 | Pride
4-oxo-2-nonenal 
UnknownInternational fisheries threaten globally endangered sharks in the Eastern Tropical Pacific Ocean: the case of the Fu Yuan Yu Leng 999 reefer vessel seized within the Galapagos Marine Reserve.
Not available
S-EPMC8298506 | biostudies-literature
UnknownCapecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
Not available
S-EPMC4050205 | biostudies-literature
ProteomicsThe EXOSC10S402T allele identified in colon cancer causes early embryonic lethality and suggests EXOSC10 as a biomarker for 5-fluorouracil sensitivity
The conserved 3’-5’ exoribonuclease EXOSC10/Rrp6 degrades and processes aberrant mRNAs and non-coding RNAs in cooperation with the RNA exosome. The protein is phosphorylated and ubiquitinated and it’s subcellular localization and stability are controlled during stress responses via sumoylation and t...
ORGANISM(S): Homo sapiens (Human) 
2026-03-20 | PXD061578 | Pride
Rrp6 5-fluorouracil Exosc10 Ubiquitination 
UnknownEnhancing Chemotherapeutic Efficacy in Lung Cancer Cells Through Synergistic Targeting of the PI3K/AKT Pathway with Small Molecule Inhibitors.
Not available
S-EPMC12428413 | biostudies-literature
UnknownGenetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.
Not available
S-EPMC4879695 | biostudies-literature
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