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ProteomicsPhosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway
In this study, we found that CB inhibited ICC cell proliferation and promoted cell apoptosis. By using phosphoproteomics, we found significant changes in the proteome and phosphorylome associated with DNA damage and apoptosis in response to CB treatment. Further investigations demonstrated that CB i...
ORGANISM(S): Homo Sapiens 
2022-06-20 | PXD034717 |
ProteomicsIdentification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
Identification of a novel bile marker Clusterin and a public online prediction platform based on deep learning for Cholangiocarcinoma
ORGANISM(S): Homo Sapiens 
2023-07-13 | PXD043745 |
TranscriptomicsReprogramming Transcriptional Responses through Functionally-Distinct Classes of Enhancers in Prostate Cancer Cells [gene expression]
Mammalian genomes are populated with thousands of transcriptional enhancers that orchestrate cell type-specific gene expression programs; however, the potential that there are pre-established enhancers in different functional classes that permit alternative signal-dependent transcriptional responses...
ORGANISM(S): Homo sapiens 
2011-05-15 | E-GEOD-27682 | biostudies-arrayexpress
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