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ProteomicsIMPRINTS-CETSA, 5-FU in parental and 5-FU-resistant HCT15 cells
Parental and 5-fluorouracil (5-FU)-resistant HCT15 cells were treated with 5-FU or vehicle for 12h and assembled into an IMPRINTS-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC, 54ºC, and 57ºC) with each set of samples heated at one temperature included in the same isobar...
ORGANISM(S): Homo Sapiens (human) 
2021-07-15 | PXD026472 | JPOST Repository
ProteomicsMCF7 xenografts with 5-FU in vivo ITDR-CETSA
MCF7 xenograft-bearing mice were treated intravenously for 22h with either vehicle or different 5-FU doses (10, 50, 100, and 150 mg/kg). Each xenograft was cut in similar-sized pieces and assembled into an ITDRCETSA scheme with 2 different heating temperatures (37ºC, 52ºC) and 3 xenograft pieces for...
ORGANISM(S): Homo Sapiens (human) 
2021-07-15 | PXD026470 | JPOST Repository
GenomicsThe Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation
The Mediator complex functions as a control center orchestrating diverse signalings, gene activities, and biological processes. However, how Mediator subunits determine distinct cell fates remains to be fully elucidated. Here, we show that Mediator MED23 controls the cell fate preference that direct...
ORGANISM(S): Mus musculus 
2012-12-20 | E-GEOD-40369 | biostudies-arrayexpress
ProteomicsIMPRINTS-CETSA, FUDR and FUR in MCF7 cells, 2h and 12h incubation
MCF7 cells were treated with floxuridine (FUDR), fluorouridine (FUR), or vehicle and assembled into an IMPRINTS-CETSA scheme with 6 different heating temperatures (37ºC, 47ºC, 50ºC, 52ºC, 54ºC, and 57ºC) with each set of samples heated at one temperature included in the same isobaric TMT10 set and m...
ORGANISM(S): Homo Sapiens (human) 
2021-07-15 | PXD026471 | JPOST Repository
UnknownComparative transcriptomic analysis of normal and abnormal in vitro flowers in Cymbidium nanulum Y. S. Wu et S. C. Chen identifies differentially expressed genes and candidate genes involved in flower formation.
Not available
S-EPMC9638074 | biostudies-literature
MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
UnknownDifferent treatment strategies and molecular features between right-sided and left-sided colon cancers.
Not available
S-EPMC4458758 | biostudies-literature
UnknownEGFR Activates a TAZ-Driven Oncogenic Program in Glioblastoma.
Not available
S-EPMC8277712 | biostudies-literature
UnknownFrondoside A Inhibits an MYC-Driven Medulloblastoma Model Derived from Human-Induced Pluripotent Stem Cells.
Not available
S-EPMC8172454 | biostudies-literature
UnknownDetecting structural variations with precise breakpoints using low-depth WGS data from a single oxford nanopore MinION flowcell.
Not available
S-EPMC8927474 | biostudies-literature
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