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ProteomicsProteomics of Fuchs Endothelial Corneal Dystrophy support that the extracellular matrix of Descemet¹s membrane is Disordered
Fuchs’ endothelial corneal dystrophy is major corneal disorder in the western world affecting the innermost part of the cornea, which leads to visual impairment. The morphological changes observed in Fuchs’ endothelial corneal dystrophy is well described, however, much less in known of the pathology...
ORGANISM(S): Homo sapiens (Human) 
2014-05-27 | PXD000746 | Pride
Itraq quantification Fuchs' endothelial corneal dystrophy Xic quantification 
ProteomicsMS-based identification of small proteins in Campylobacter jejuni
The Gram-negative bacterium Campylobacter jejuni is a widespread food-borne pathogen. Knowing the proteins encoded by the bacterial pathogen and how their expression is regulated is essential to understand how it survives, colonizes, and causes diseases. The present study focusses on small proteins...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 
2024-05-23 | PXD036790 | Pride
Ribosome profiling Gelfree fractionator Sorf Small proteins Gelc-ms/ms Campylobacter jejuni Translatome 
ProteomicsTCF4 trinucleotide repeat expansion drives distinct proteomic signatures in Fuchs endothelial corneal dystrophy
The aims of this study were to use an isogenic cell model system to investigate the proteomic consequences of TCF4 trinucleotide repeat expansion in Fuchs endothelial corneal dystrophy (FECD) and to identify potential molecular pathways contributing to disease pathogenesis. We used our previously es...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD075094 | Pride
Retina Fuchs endothelial corneal dystrophy (fecd) Ctg repeat 
GenomicsA Genome-Wide Association Study of Fuchs' Endothelial Corneal Dystrophy (FECD)

Fuchs' Endothelial Corneal Dystrophy (FECD) is a common disease that results in loss of vision associated with progressive corneal edema and loss of corneal transparency. In the initial stages of the disease, excrescences on Descemet's membrane with the appearance of an abnormal posterior...

phs000421.v1.p1 | EGA
TranscriptomicsIdentification of the fludioxonil-responsive genes dependent on SskA, SrrA, HogA, and AtfA in Aspergillus nidulans
Microarray analysis was used to identify the fludioxonil-responsive genes dependent on SskA, SrrA, HogA, and AtfA in the filamentous fungus Aspergillus nidulans. In order to identify such genes, we conducted the several types of experiment. One was a comparison between wild type treated with fludio...
ORGANISM(S): Emericella nidulans 
2009-06-09 | E-GEOD-16509 | biostudies-arrayexpress
ProteomicsAscorbic acid and TGF-B differentially effect on ECM elaborated by the corneal endothelial cells
Fuchs endothelial corneal dystrophy FECD is a progressive corneal disease that impacts the structure and stiffness of the Descemets membrane DM, a protein layer that serves as a matrix for the corneal endothelial cells CECs. These structural alterations of the DM contribute to the loss of the CECs r...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
MSV000088172 | MassIVE
ProteomicsProtein co-immmunoprecipitation using antibodies specific for the antimicrobial peptide FsPDF2 from Fagus sylvatica
To assess the specificity of the antibodies used in the quantitative sandwich ELISA, co-immunoprecipitation (CoIP) was performed. Proteins binding to these antibodies were detected using LC-MS/MS in DDA mode.
ORGANISM(S): Fagus sylvatica 
2026-06-08 | PXD060631 | Pride
Co- immunoprecipitation (coip) Antimicrobial peptides Fagus sylvatica 
ProteomicsBPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection
The anaerobic spirochete Brachyspira causes intestinal spirochetosis, characterized by the intimate attachment of bacterial cells to the colonic mucosa, potentially leading to symptoms such as diarrhea, abdominal pain, and weight loss. Despite the clinical significance of Brachyspira infections, the...
ORGANISM(S): Homo sapiens (Human) Brachyspira pilosicoli P43/6/78 
2024-10-18 | PXD056942 | Pride
Brachyspira pilosicoli  caco-2 cells  ibs  adhesin  intestinal epithelial cells  outer membrane proteins  tight junctions 
TranscriptomicsBrugia pahangi mature vs immature microfilariae
Filarial nematodes are arthropod-borne nematodes that cause a variety of economically important diseases such as onchocerciasis (river blindness), lymphatic filariasis, and heartworm disease. The most widespread filarial disease of humans is lymphatic filariasis, caused by worms in the genera Wuche...
ORGANISM(S): Brugia pahangi 
2010-05-22 | E-GEOD-14939 | biostudies-arrayexpress
UnknownMeiotic segregation and post-meiotic drive of the Festuca pratensis B chromosome.
Not available
S-EPMC10474989 | biostudies-literature
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