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TranscriptomicsExpression data from skin biopsy samples from patients with moderate-to-severe psoriasis
A gene expression profiling sub-study was conducted in which skin biopsy samples were collected from 85 patients with moderate-to-severe psoriasis who were participating in ACCEPT, an IRB-approved Phase 3, multicenter, randomized trial. This analysis identified 4,175 probe-sets as being significantl...
ORGANISM(S): Homo sapiens 
2012-07-25 | E-GEOD-30999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human moncyte derived dendritic cells grown with/without Etanercept TNF inhibitor
The process for making monocyte derived DCs (moDCs) has been previously described (46). All analysis was performed on “day 5” immature DCs. Etanercept 10mg/mL was added to experimental wells on days 0, 2, and 4. We chose this concentration of etanercept as it approximates the plasma concentra...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9239 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of acute and chronic atopic dermatitis compared to normal skin
Atopic dermatitis (AD) is a common disease, with an increasing prevalence. The primary pathogenesis of the disease is still elusive, resulting in lack of specific treatments. The prevailing view is that AD is a biphasic, T-cell polarized disease, with Th2 predominating acute AD, and a switch to Th1 ...
ORGANISM(S): Homo sapiens 
2012-09-21 | E-GEOD-36842 | biostudies-arrayexpress
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