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UnknownFOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer.
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S-EPMC4988311 | biostudies-literature
TranscriptomicsCarboxypeptidase of glutamate-like gene as a tumor suppressor in pancreatic cancer cells and a prognostic marker for resected pancreatic cancer patients
Pancreatic cancer is the fourth leading cancer-related death in United States. The clinical relevance of genomic imbalances in pancreatic cancer is uncertain. We performed array-comparative genomic hybridization (aCGH) in 44 resected pancreatic cancer specimens from a Korean cohort. We observed recu...
ORGANISM(S): Homo sapiens 
2011-04-21 | E-GEOD-28732 | biostudies-arrayexpress
TranscriptomicsCrizotinib inhibits metabolic inactivation of gemcitabine in ortothopic pancreatic tumors derived from primary cells with c-Met overexpression
Pancreatic ductal adenocarcinoma (PDAC) remains a major unsolved health problem. Most drugs that pass preclinical tests fail in these patients, emphasizing the need of appropriate preclinical models to test novel anticancer strategies. We developed four orthotopic mouse models employing primary huma...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-44587 | biostudies-arrayexpress
TranscriptomicsHigh-throughput microRNA (miRNAs) arrays in pancreatic cancer
Background: Only a subset of radically-resected pancreatic ductal adenocarcinoma (PDAC) patients benefit from chemotherapy, and identification of novel prognostic factors is warranted. Recently miRNAs emerged as diagnostic biomarkers and innovative therapeutic targets, while high-throughput arrays a...
ORGANISM(S): Homo sapiens 
2012-11-22 | E-GEOD-38781 | biostudies-arrayexpress
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