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ModelsBarr2016 - All-or-nothing G1/S transition
Barr2016 - All-or-nothing G1/S transition This model is described in the article: A Dynamical Framework for the All-or-None G1/S Transition. Barr AR, Heldt FS, Zhang T, Bakal C, Novák B. Cell Syst 2016 Jan; 2(1): 27-37 Abstract: The transition from G1 into DNA replica...
2024-09-02 | BIOMD0000000646 | BioModels
ProteomicsTHE FAM53C/DYRK1A AXIS REGULATES THE G1/S TRANSITION OF THE CELL CYCLE
A growing number of small molecules are becoming available to target the cell cycle machinery for the treatment of cancer and other human diseases. Consequently, a greater understanding of the factors regulating cell cycle progression becomes essential to help enhance to response of patients to thes...
ORGANISM(S): Homo sapiens (Human) 
2026-04-23 | PXD055829 | Pride
G1/s transition Cell cycle 
ModelsSwat2004_Mammalian_G1_S_Transition
This is the extended model described the article: Bifurcation analysis of the regulatory modules of the mammalian G1/S transition. Swat M, Kel A, Herzel H. Bioinformatics 2004 Jul 10;20(10):1506-11. PMID: 15231543 , doi: ...
2024-09-02 | BIOMD0000000228 | BioModels
ModelsKollarovic2016 - Cell fate decision at G1-S transition
Kollarovic2016 - Cell fate decision at G1-S transition This model is described in the article: To senesce or not to senesce: how primary human fibroblasts decide their cell fate after DNA damage. Kollarovic G, Studencka M, Ivanova L, Lauenstein C, Heinze K, Lapytsko A, Talem...
2024-09-02 | BIOMD0000000632 | BioModels
ModelsHatzimanikatis1999-Regulation of the G1-S transition of the mammalian cell cycle.
A mathematical model of regulation of the G1-S transition of the mammalian cell cycle has been formulated to organize available experimental molecular-level information in a systematic quantitative framework and to evaluate the ability of this manifestation of current knowledge to calculate correctl...
2020-05-07 | MODEL2005070001 | BioModels
ProteomicsThe role of Cdk1-cyclin B in G1/S transition revealed by chemical genetic inhibition of Cdc7
Entry of mammalian cells into DNA synthesis (S-phase) represents a key event in cell division. According to the current cell cycle models, the Cdc7 kinase represents the essential and rate-limiting trigger of DNA replication, acting together with the cyclin-dependent kinase Cdk2. Using chemical gene...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-11 | PXD025625 | Pride
Cdk1-cyclinb G1/s transition Cdc7 Dna replication 
ModelsChiorino2002 - G1/S transition model
mathematical approach to model the protein interactions regulating the transition from the G1 phase to the phase of DNA synthesis. Model is encoded by matthieu Maire and submitted to BioModels by krishna kumar tiwari.
2020-03-19 | MODEL2003180003 | BioModels
GenomicsThe FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
PRJNA1191063 | ENA
GenomicsCENPF overexpression facilitates the G1/S cell cycle transition of hepatocellular carcinoma cells via MYC pathway
CENPF overexpression facilitates the G1/S cell cycle transition of hepatocellular carcinoma cells via MYC pathway
PRJNA1425118 | ENA
GenomicsSNHG17 Interacts with LRPPRC to Stabilize c-Myc and Promote G1/S Transition and Cell Proliferation
SNHG17 Interacts with LRPPRC to Stabilize c-Myc and Promote G1/S Transition and Cell Proliferation
PRJNA700980 | ENA
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