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ProteomicsComplex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing
GABAB receptors (GBRs) are key regulators of synaptic release but little is known about trafficking mechanisms that control their presynaptic abundance. We now show that sequence-related epitopes in APP, AJAP-1 and PIANP bind with nanomolar affinities to the N-terminal sushi-domain of presynaptic GB...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-13 | PXD012487 | Pride
Gabab receptors Cellular neuroscience Lc-ms/ms 
UnknownDiscovery of a Negative Allosteric Modulator of GABAB Receptors.
Not available
S-EPMC4094264 | biostudies-literature
UnknownRedistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.
Not available
S-EPMC6729668 | biostudies-literature
UnknownTransient Activation of GABAB Receptors Suppresses SK Channel Currents in Substantia Nigra Pars Compacta Dopaminergic Neurons.
Not available
S-EPMC5201262 | biostudies-literature
UnknownSpinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats.
Not available
S-EPMC7378325 | biostudies-literature
TranscriptomicsRegulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets
G protein-coupled receptors (GPCRs) are seven transmembrane signaling molecules that are involved in a wide variety of physiological processes. They constitute a large protein family of receptors with almost 300 members detected in human pancreatic islet preparations. However, the functional role of...
ORGANISM(S): Homo sapiens 
2020-08-01 | GSE155482 | GEO
GenomicsRegulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets
Regulated expression and function of the GABAB receptor in human pancreatic beta cell line and islets
PRJNA649918 | ENA
UnknownGABAB receptors role in cell migration and positioning within the ventromedial nucleus of the hypothalamus.
Not available
S-EPMC2292832 | biostudies-literature
UnknownAssociation of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.
Not available
S-EPMC4060866 | biostudies-literature
UnknownNatural Product Isoliquiritigenin Activates GABAB Receptors to Decrease Voltage-Gate Ca2+ Channels and Glutamate Release in Rat Cerebrocortical Nerve Terminals.
Not available
S-EPMC8534184 | biostudies-literature
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