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ProteomicsLoss of GABAergic D-type motor neurons in young adult Caenorhabditis elegans after exposition with silica nanoparticles
Although C. elegans is commonly used to assess the neurotoxicity of environmental pollutants, studies that explore the intricate biology of its nervous system, particularly those addressing long term effects and aging in adult worms, are rare. These models offer significant advantages for understand...
ORGANISM(S): Caenorhabditis elegans 
2025-03-25 | PXD056717 | Pride
Nanoscale silica C. elegans Neurodegeneration Environmental pollutants Gabaergic d-type motor neurons 
TranscriptomicsInduction of cells expressing markers of GABAergic neurons by transcription factors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-21 | E-GEOD-78951 | biostudies-arrayexpress
UnknownDietary Transfer of Zinc Oxide Nanoparticles Induces Locomotive Defects Associated with GABAergic Motor Neuron Damage in Caenorhabditis elegans.
Not available
S-EPMC9866546 | biostudies-literature
UnknownLoss of γ-aminobutyric acid D-Type Motor Neurons in Young Adult <i>Caenorhabditis elegans</i> Following Exposition with Silica Nanoparticles.
Not available
S-EPMC11816968 | biostudies-literature
UnknownTherapeutic potential of 5HT2CR in alleviating spasticity and pain via modulation of motor neurons and interneurons in spinal cord injury.
Not available
S-EPMC12475576 | biostudies-literature
UnknownChannel-independent function of UNC-9/Innexin in spatial arrangement of GABAergic synapses in C. elegans.
Not available
S-EPMC9665852 | biostudies-literature
TranscriptomicsBulk RNA-seq expression data isolated from early L4 stage C. elegans larvae
During development C. elegans GABAergic dorsal D-class (DD) motor neurons reverse polarity such that the axonal and dendritic compartments are switched. We found that the gene DVE-1 is important for this process. To elucidate potential targets of dve-1 transcriptional regulation we conducted bulk RN...
ORGANISM(S): Caenorhabditis elegans 
2024-12-08 | GSE218350 | GEO
TranscriptomicsBulk RNA-seq expression data isolated from early L1 stage C. elegans larvae
During development C. elegans GABAergic dorsal D-class (DD) motor neurons reverse polarity such that the axonal and dendritic compartments are switched. We found that the gene DVE-1 is important for this process. To elucidate potential targets of dve-1 transcriptional regulation we conducted bulk RN...
ORGANISM(S): Caenorhabditis elegans 
2024-12-08 | GSE218349 | GEO
TranscriptomicsGene expression alterations in the cerebellum and granule neurons of Cstb-/- mouse are associated with early synaptic changes and inflammation
Progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1) is an inherited neurodegenerative disease with myoclonus, seizures and ataxia, caused by the mutations in cystatin B (CSTB) gene. In an approach towards understanding the molecular basis of pathogenic events in EPM1 we have utilized t...
ORGANISM(S): Mus musculus 
2014-03-03 | E-GEOD-47516 | biostudies-arrayexpress
UnknownComprehensive Gene Expression Analysis Using Human Induced Pluripotent Stem Cells Derived from Patients with Sleep Bruxism: A Preliminary In Vitro Study.
Not available
S-EPMC11642595 | biostudies-literature
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