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GenomicsThe Genomic Binding Profile of GAGA Element Associated Factor (GAF) in Drosophila S2 cells
GAGA associated transcription factor (GAF) is a highly abundant and essential protein in Drosophila. GAF recognizes and binds arrays of GA dinucleotides via a zinc finger DNA binding domain to regulate transcription by binding to general TF machinery or recruit nucleosome remodeling factors. We perf...
ORGANISM(S): Drosophila melanogaster 
2013-08-01 | E-GEOD-40646 | biostudies-arrayexpress
ProteomicsA GAF domain mediates inositol pyrophosphate substrate channeling in PPIP5K phosphatases
Inositol pyrophosphates are highly phosphorylated nutrient messengers. The final step of their biosynthesis is catalyzed by diphosphoinositol pentakisphosphate kinase (PPIP5K) enzymes, which are conserved among fungi, plants, and animals. PPIP5Ks contain an N-terminal kinase domain that generates th...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-10-07 | PXD056020 | Pride
Inositol pyrophosphate Schizosaccharomyces pombe Histidine acid phosphatase Arabidopsis thaliana. hdx-ms Phytase Saccharomyces cerevisiae Enzyme mechanism Phosphate homeostasis Gaf domain Inositol pyrophosphate phosphatase 
UnknownA GAF-domain-regulated adenylyl cyclase from Anabaena is a self-activating cAMP switch.
Not available
S-EPMC126120 | biostudies-literature
UnknownCoevolving residues distant from the ligand binding site are involved in GAF domain function.
Not available
S-EPMC11977230 | biostudies-literature
UnknownStructure and function of the juxtamembrane GAF domain of potassium biosensor KdpD.
Not available
S-EPMC7454560 | biostudies-literature
UnknownCyclic nucleotide binding and structural changes in the isolated GAF domain of Anabaena adenylyl cyclase, CyaB2.
Not available
S-EPMC4411481 | biostudies-literature
UnknownConformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain.
Not available
S-EPMC2992248 | biostudies-literature
UnknownStructural rearrangement accompanying ligand binding in the GAF domain of CodY from Bacillus subtilis.
Not available
S-EPMC3128921 | biostudies-literature
UnknownPDE5 is converted to an activated state upon cGMP binding to the GAF A domain.
Not available
S-EPMC140735 | biostudies-literature
UnknownStructure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.
Not available
S-EPMC314001 | biostudies-literature
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