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TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells
This SuperSeries is composed of the following subset Series: GSE36242: Transcriptomic response to benzo[a]pyrene treatment in HepG2 cells (RNA-Seq) GSE36243: Transcriptomic response to benzo[a]pyrene treatment in HepG2 cells (Affymetrix) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36244 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (RNA-Seq)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36242 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (Affymetrix)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36243 | biostudies-arrayexpress
TranscriptomicsBenzo[a]pyrene-induced changes in microRNA-mRNA networks
The microarray contains 9360 reporters, each present four times on the microarray. In our analysis 1326 human and viral reporters were used, of which 880 are unique human mature microRNAs. The other 8024 reporters represent microRNAs from other species. cDNA was generated using 1 M-NM-
ORGANISM(S): Homo sapiens 
2012-08-06 | E-GEOD-31252 | biostudies-arrayexpress
TranscriptomicsLow dose human APAP exposure
Acetaminophen is the primary cause of acute liver toxicity in Europe/USA. Therefore, the FDA reconsiders recommendations concerning safe acetaminophen dosage/use. Current tests for liver toxicity are no ideal predictive markers for liver injury. Here, ‘omics techniques (global analysis of metabolomi...
ORGANISM(S): Homo sapiens 
2011-07-07 | E-GEOD-30418 | biostudies-arrayexpress
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