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In this present project, we aimed to physiologically dissect the contribution of glycolipid- and lectin-driven endocytosis mechanism that operate within the mice intestine. We therefore decided to first characterize the expression profile of galectins in this tissue and then to focus on the specific...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-07 | PXD016499 | Pride
Galectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.
Genomics
Galectins and nanobodies on cancer cells
Our laboratory previously reported that galectins may act as parasite recognizing molecules (Leishmania) (JBC 277:17663 and JBC 278:22223). Now we are studying the role of galectin-3 in leishmaniasis in vivo, using G3KO mice.
ORGANISM(S): Mus musculus 
2011-09-06 | GSE31925 | GEO
The reading of glycan-encoded signals by tissue lectins is considered a major route of the flow of biological information in many (patho)physiological processes. The arising challenge for current research is to proceed from work on a distinct protein to family-wide testing of lectin function. Having...
ORGANISM(S): Homo sapiens 
2021-02-17 | GSE131822 | GEO
Dr. Liu's research group is interested in studying the expression and functions of galectin-3, -7 and -12, in particular the roles of these proteins in inflammation and neoplasm. Members of the galectin family are known to participate in cellular homeostasis by modulating cell growth, controlling ce...
ORGANISM(S): Homo sapiens Mus musculus 
2011-03-02 | GSE27599 | GEO
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