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ProteomicsProbing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines
The GalNAc-type O-glycoproteome is orchestrated by a large family of polypeptide GalNAc-transferase isoenzymes (GalNAc-Ts) with partially overlapping contributions to the O-glycoproteome as well as distinct non-redundant functions. Increasing evidence indicate that individual GalNAc-Ts co-regulate a...
ORGANISM(S): Homo sapiens (Human) 
2018-10-16 | PXD010155 | Pride
Inducible expression Galnac-transferase O-glycosylation Glycoproteomics Mass spectrometry 
TranscriptomicsmicroRNA-mediated GALNT3 upregulation facilitates mucin production and viral replication in influenza A virus-infected respiratory epithelial cells
Viral infections affecting the upper or lower respiratory tract induce mucin production in the epithelial surfaces of the respiratory cells. However, a little is known about how mucins are produced on the surfaces of respiratory epithelial cells and affects viral replication. In the course of the in...
ORGANISM(S): Homo sapiens 
2015-12-08 | E-GEOD-57508 | biostudies-arrayexpress
UnknownA UDP-HexNAc:polyprenol-P GalNAc-1-P transferase (WecP) representing a new subgroup of the enzyme family.
Not available
S-EPMC3133024 | biostudies-literature
UnknownA computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2.
Not available
S-EPMC4744471 | biostudies-literature
UnknownConservation of peptide acceptor preferences between Drosophila and mammalian polypeptide-GalNAc transferase ortholog pairs.
Not available
S-EPMC2574660 | biostudies-literature
UnknownO-glycosylation modulates proprotein convertase activation of angiopoietin-like protein 3: possible role of polypeptide GalNAc-transferase-2 in regulation of concentrations of plasma lipids.
Not available
S-EPMC2978557 | biostudies-literature
TranscriptomicsDeconstruction of O-glycosylation – Polypeptide GalNAc-T Isoforms Direct Distinct Subsets of the O-Glycoproteome
GalNAc-transferase (GalNAc-T) isoforms modify distinct subsets of the O-glycoproteome and GalNAc-type O-glycosylation is found on most proteins trafficking through the secretory pathway in metazoan cells. The O-glycoproteome is regulated by up to 20 polypeptide GalNAc-Ts and the contributions and bi...
ORGANISM(S): Homo sapiens 
2015-09-30 | E-MTAB-3844 | biostudies-arrayexpress
UnknownProbing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines.
Not available
S-EPMC6295722 | biostudies-literature
UnknownOverexpression of the cytotoxic T cell GalNAc transferase in skeletal muscle inhibits muscular dystrophy in mdx mice.
Not available
S-EPMC122819 | biostudies-literature
ProteomicsDeconstruction of protein O-glycosylation
GalNAc-transferase (GalNAc-T) isoforms modify distinct subsets of the O-glycoproteome and GalNAc-type O-glycosylation is found on most proteins trafficking through the secretory pathway in metazoan cells. The O-glycoproteome is regulated by up to 20 polypeptide GalNAc-Ts and the contributions and bi...
ORGANISM(S): Homo sapiens (Human) 
2015-08-21 | PXD002770 | Pride
Galnt/ dimethylation/ apolipoproteins/ mass spectrometry 
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