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TranscriptomicsHuman lung adenocarcinoma NCI-H1975 cells: parental vs cell lines resistant to the EGFR-TK inhibitor CNX-2006
Genome variation profiling of lung adenocarcinoma cells comparing untreated NCI-H1975 cells with CNX-2006-resistant untreated cells. Goal was to determine the potential mechanism of resistance to mutant EGFR-TKIs and rationally design novel strategies for the treatment of EGFR-mutant lung cancer pat...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-53234 | biostudies-arrayexpress
UnknownSurvival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses.
Not available
S-EPMC3528377 | biostudies-literature
UnknownIdentification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants.
Not available
S-EPMC5334540 | biostudies-literature
TranscriptomicsCrizotinib inhibits metabolic inactivation of gemcitabine in ortothopic pancreatic tumors derived from primary cells with c-Met overexpression
Pancreatic ductal adenocarcinoma (PDAC) remains a major unsolved health problem. Most drugs that pass preclinical tests fail in these patients, emphasizing the need of appropriate preclinical models to test novel anticancer strategies. We developed four orthotopic mouse models employing primary huma...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-44587 | biostudies-arrayexpress
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