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ProteomicsBeyond Inhibition - Sub-lethal Rifampicin-induced molecular adaptations confer phenotypic drug tolerance in Mycobacteria
This study investigates how sub-lethal concentrations of rifampicin act as a signalling stimulus that induces phenotypic drug tolerance in mycobacteria. Using Mycobacterium smegmatis as a fast-growing model and validating findings in the attenuated Mycobacterium tuberculosis H37Ra strain, we examine...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Bacteria Mycobacterium tuberculosis H37Ra 
2026-06-08 | PXD075873 | Pride
ProteomicsProteomic analysis of human macrophages overexpressing angiotensin-converting enzyme
Angiotensin converting enzyme (ACE) exerts strong modulation of myeloid cell function independently of its cardiovascular arm. The success of the ACE-overexpressing murine macrophage model, ACE 10/10, in treating microbial infections and cancer opens a new venture into whether ACE overexpression in ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD052292 | Pride
Ace Swath Protein inhibitor Angiotensin Protein function 
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